[Rhabdomyolysis after isotretinoin treatment in a 17-year-old male].

Rhabdomyolysis is a rare, but known complication to treat-ment with systemic isotretinoin in patients with acne and can lead to severe kidney damage. In our case report a 17-year-old male, exercising moderately, developed rhab-domyolysis without kidney injury after two-month treatment with isotretinoin 20 mg daily. He complained of some muscle pain and was treated according to guidelines for rhabdomyolysis with no sequelae.

The Danish Nonmelanoma Skin Cancer Dermatology Database.

Aim Of Database: The Danish Nonmelanoma Skin Cancer Dermatology Database was established in 2008. The aim of this database was to collect data on nonmelanoma skin cancer (NMSC) treatment and improve its treatment in Denmark. NMSC is the most common malignancy in the western countries and represents a significant challenge in terms of public health management and health care costs.

Topical corticosteroid has no influence on inflammation or efficacy after ingenol mebutate treatment of grade I to III actinic keratoses (AK): A randomized clinical trial.

Background: Ingenol mebutate (IngMeb) is approved for treatment of actinic keratoses (AK) and may cause unpredictable local skin responses (LSR).

Objectives: We sought to investigate whether IngMeb-induced LSR, pain, and pruritus could be alleviated with a topical glucocorticoid and, further, to assess efficacy, cosmetic outcome, and patient satisfaction in patients with severe photodamage.

Methods: In this blinded, randomized controlled clinical trial, patients with multiple AK and field cancerization of the face or scalp were treated in 2 areas with IngMeb (0.

[Treatment by non-physicians of skin diseases--including potentially malignant diseases with lasers and intense pulsed light].

Introduction: Laser and IPL treatment by non-physicians raises professional concern. The purpose of this investigation is to evaluate laser and IPL treatment carried out by non-physicians and to assess the level of pre-treatment information given to patients.

Material And Methods: Approached clinics were found by internet-searches and from advertisements in telephone directories and national newspapers.

Ultrastructural alteration of tape-stripped normal human skin after photodynamic therapy.

The effect of photodynamic therapy on tape-stripped normal human skin was explored ultrastructurally. Back skin areas of 3 healthy Caucasian volunteers, 2 men and 1 woman, were tape-stripped 10 consecutive times followed by topical treatment with 5-aminolevulinic acid (20%, w/w) for 4 hours under occlusion (Tegaderm). Then the areas were irradiated for 30 minutes with Waldman PDT 1200 lamp (570-650 nm) with a total dose of 70 J/cm(2).

Pain associated with photodynamic therapy using 5-aminolevulinic acid or 5-aminolevulinic acid methylester on tape-stripped normal skin.

Background: Pain during and after topical photodynamic therapy (PDT) is one of the few severe adverse effects of the new treatment of skin diseases.

Objective: To compare the pain experienced in normal skin treated with 5-aminolevulinic acid (ALA) PDT and 5-aminolevulinic methylester (ALA-ME) PDT.

Design: Double-blind randomized trial.

Autofluorescence spectrum of skin: component bands and body site variations.

BACKGROUND/AIMS: The autofluorescence spectrum of skin consists of a number of overlapping single spectra emitted by fluorescent molecules. The overlapping makes it difficult to distinguish changes in the overall spectrum and the molecular basis for it. We applied curve fitting analysis to decompose the autofluorescence spectrum of normal human skin and studied the variation in different body sites.