Publications by authors named "Ichro Yokoe"
Article Synopsis
- Phenylpropanoids, like bis-FA (compound 2), have shown promise as NSAID-like anti-inflammatory agents.
- In experiments, bis-FA significantly inhibited COX-2 expression in LPS-stimulated RAW 264.7 cells, unlike ferulic acid (compound 1), which did not demonstrate this effect.
- The compounds also exhibited varying levels of anti-radical activity, with bis-FA showing stronger COX-2 inhibition but weaker radical scavenging compared to ferulic acid, indicating a potential trade-off in their anti-inflammatory capabilities.
