Publications by authors named "Icaro Rodrigues Dos Santos"

Molecular diagnosis of bovine tuberculosis plays an essential role in the epidemiological knowledge of the disease. Bovine tuberculosis caused by represents a risk to human health. This study aimed to perform the genotypic characterization of isolated from bovines diagnosed as tuberculosis from dairy herds in the state of Pernambuco, Brazil.

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Mycobacterium haemophilum is a nontuberculous mycobacterium that causes localized or disseminated disease, mainly in immunocompromised hosts. We report the case of a 35-year-old HIV-infected woman who presented with several enlarging cutaneous lesions over the arms and legs. Histopathological examination revealed the diagnosis of a cutaneous mycobacterial disease.

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Article Synopsis
  • TB-SPRINT is a microbead-based assay designed for rapid detection of tuberculosis and multidrug-resistant TB, aiming to improve clinic and research laboratory outcomes.
  • The study evaluated TB-SPRINT's performance against established systems, showing its accuracy in detecting rifampicin and isoniazid resistance ranged from 81% to 99%.
  • Despite promising results, further enhancements are necessary for TB-SPRINT to meet In Vitro Diagnostics standards, with costs calculated at approximately USD 127.78 for mean cost and USD 109.94 for activity-based costing.
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Chagas disease is still a major public health issue in many Latin American countries. One of the current major challenges is to find an association between Trypanosoma cruzi discrete typing units (DTUs) and clinical manifestations of the disease. In this study, we used a multilocus conventional PCR and quantitative real time PCR (qPCR) approaches to perform the molecular typing and parasite load quantification directly from blood specimens of 65 chronic Chagas disease patients.

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