Publications by authors named "Ibtissam Laib"

Peptic ulcer disease remains a prevalent gastrointestinal disorder worldwide. Current treatments often have limitations, sparking interest in alternative therapies from medicinal plants. This review examines the gastroprotective potential of 54 North African medicinal plants against peptic ulcers.

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Article Synopsis
  • Silver nanoparticles (Ag/Ag₂O NPs) have shown strong antioxidant and antimicrobial properties, making them potentially useful for treating chemical-induced toxicity.
  • The study aimed to create these nanoparticles using olive leaf extract and assess their protective effects on Wistar rats exposed to metribuzin, focusing on oxidative stress and blood parameters.
  • Results indicated that the lower dose of the nanoparticles significantly improved various blood metrics and lipid levels, while the higher dose had mixed effects, suggesting dose optimization is crucial for therapeutic applications.
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This study investigates the wound-healing potential of Euphorbia guyoniana latex (EGL) in male Wistar rats, along with its biochemical composition and biological activities. Phytochemical analysis identified moderate levels of phenolics, flavonoids, and tannins, with HPLC revealing five phenolic compounds. EGL demonstrated strong antioxidant activity in DPPH assays, surpassing ascorbic acid in protecting red blood cells.

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  • * A total of 65 peaks were identified, revealing 6 major bioactive compounds, with varying concentrations of polyphenols, flavonoids, and tannins.
  • * The aqueous extract showed strong antioxidant activities, high anti-inflammatory effects, and moderate antibacterial properties against five strains, demonstrating its potential health benefits.
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This study explored the therapeutic efficacy of and silver nanoparticles (Ag NPs) synthesized using a extract to alleviate cadmium-induced nephrotoxicity in Wistar rats. Sub-acute toxicity assessments of (100 mg/kg, 1000 mg/kg, and 4000 mg/kg) and Ag NPs (2 mg/kg and 10 mg/kg) did not find any significant difference, compared with untreated control rats ( = 3 animals/group). Then, the adult Wistar rats were divided into one control (untreated/unexposed) and six experimental groups ( = 5/group): Ag NPs alone, alone, exposure to 50 mg/kg CdCl in drinking water for 35 days, exposure to CdCl for 35 days followed by treatment with 0.

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This study explores the therapeutic potential of silver nanoparticles (Ag NPs) synthesized using a extract in mitigating cadmium-induced hepatotoxicity in Wistar rats. Given the increasing environmental and health concerns associated with cadmium exposure, novel and eco-friendly therapeutic strategies are essential. Ag NPs were characterized using X-ray diffraction, UV-Vis spectrometry, and energy-dispersive X-ray spectroscopy with scanning electron microscopy, confirming their formation with a cubic crystal structure and particle sizes ranging from 4.

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