Publications by authors named "Ibtihal Omer"
Article Synopsis
- Cryptococcus neoformans is a major fungal pathogen prioritized by the WHO, prompting research into a new multi-epitope vaccine based on its mannoprotein antigen (MP88) using computational methods.
- In the study, several promising B-cell and T-cell epitopes were identified, including specific sequences for CD8+ and CD4+ T-cells that have potential for vaccine development.
- The vaccine candidate was further developed to be stable, non-toxic, and soluble, and its genetic material was successfully cloned into an E. coli vector for potential expression and testing.
Introduction: Tuberculosis (TB) and diabetes mellitus (DM) are both important health issues, and the association between DM and TB may be the next challenge for global TB control worldwide, type 2 DM (T2DM) responsible for 90% of DM cases. Persons with diabetes have a significantly increased risk of active TB, which is two to three times higher than in persons without diabetes. The aim of this study was to determine the association between pulmonary tuberculosis (PTB) and T2DM among Sudanese patients and also to determine the association between hemoglobin A1c (HbA1c) percentage in diabetic patients and development of PTB and effect of duration of T2DM in developing PTB.
View Article and Find Full Text PDFBackground: Patients with cirrhotic ascites (PCA) are susceptible to spontaneous bacterial peritonitis (SBP) which has increased morbidity and mortality. Since some host defense aspects of peritoneal macrophages (PMф) from PCA are altered this study examined factors related to receptor-mediated phagocytosis.
Methods: Twelve PCA were studied.