Factors associated with oocyte recovery rates during in-vitro fertilization among Nigerian women.

Introduction: the availability of oocytes is fundamental to in vitro fertilization (IVF). The factors associated with optimal or suboptimal oocyte recovery rates (ORR) in low-resource settings are not well known. This study aimed to determine the factors associated with ORR by comparing demographic and IVF cycle data of women undergoing IVF in our Centre.

The status of ART in the public health sector in Africa: a multi-country survey.

Research Question: What is the current availability of treatment with assisted reproductive technology (ART) in the public sector in Africa, and what are the facilitators and barriers towards its provision?

Design: Cross-sectional quantitative and qualitative data were collected in two phases from February 2020 to October 2021. Key informants were identified from countries known to provide ART in Africa based on data from the African Network and Registry for Assisted Reproductive Technology and the 2019 Surveillance from the International Federation of Fertility Societies. Quantitative data were collected via a structured questionnaire (Phase 1); public centre-specific quantitative and qualitative data were then collected via a semi-structured questionnaire followed by a virtual interview (Phase 2).

Trends in semen parameters of infertile men in South Africa and Nigeria.

There are conflicting reports on trends of semen parameters from different parts of the globe. However, in recent times there is dearth of information on the trend in Sub-Saharan countries. Therefore, in this study we aimed at determining the trends in semen parameters in Nigeria and South Africa between 2010 and 2019.

Correlation of female age with outcome of IVF in a low-resource setting.

Objective: To determine the effect of female age on pregnancy outcome after in vitro fertilization/embryo transfer (IVF-ET).

Methods: A prospective study was conducted involving 266 women who had IVF-ET at Nisa Fertility and Genetic Center, Abuja, Nigeria. All eligible consenting women were recruited to the study.

Live birth following preimplantation genetic testing to prevent sickle cell disease in a low resource setting: A case report.

Preimplantation genetic testing for monogenic disorders (PGT-M) can detect sickle cell disease (HbSS) in embryos during In-Vitro Fertilization (IVF), to ensure the birth of unaffected children. The prevalence of haemoglobin S gene (HbS) is high in Nigeria and Sub-Saharan Africa, but access to PGT-M services in the setting is limited. A couple with the sickle cell trait (HbAS) had IVF, following which 12 embryos were biopsied and the corresponding cells analyzed using minisequencing for whole genome amplification and polymerase chain reaction (PCR) to determine each embryo's haemoglobin (Hb) genotype.

Hepatitis B and C virus co-infection in Nigerian patients with HIV infection.

Introduction: We set out to determine the seroprevalence of hepatitis B and hepatitis C viruses among human immunodeficiency virus infected individuals and its impact on pattern of presentation.

Methodology: A serological study for hepatitis B and hepatitis C viruses was performed on 260 HIV-positive individuals. These patients were tested for the presence of hepatitis B surface antigen and anti-hepatitis C virus (HCV) antibody.