Objective: To study the effect of splenectomy in patients with thalassemia major on the cardiovascular system through echocardiographic study.
Methods: A prospective, cross sectional study was carried out from December 2006 to December 2007. Patients from the Thalassemia Center in the Maternity and Children's Hospital, Madina, Kingdom of Saudi Arabia, were screened by means of history, physical examination, laboratory studies, and echocardiography.