Selectin Dependence of Allergic Skin Inflammation Is Diminished by Maternal Atopy.

Allergic skin inflammation requires the influx of inflammatory cells into the skin. Extravasation of leukocytes into the skin requires interactions between endothelial selectins and their glycan ligands on the surface of leukocytes. Selectin-ligand formation requires the activity of several glycosyltransferases, including In this report, we tested the importance of for the development of allergic skin inflammation in the Stat6VT transgenic mouse model.

Urging health system research: identifying gaps and fortifying tuberculosis control in Pakistan.

Aim: To assess the significance of health system research in reducing the burden of tuberculosis and improving the performance of National Tuberculosis Control Program in Pakistan.

Method: Qualitative and quantitative content analysis of research papers on tuberculosis and influence of the research knowledge on the efficiency of the National Tuberculosis Control Program.

Results: We analyzed 268 research papers on tuberculosis in Pakistan published in the 1960-2002 period, from both national and international perspectives.

Burden of tuberculosis in Afghanistan: update on a war-stricken country.

Aim: To review Afghans Tuberculosis (TB) Control Program and assesses the impact of disruption induced by the war in Afghanistan.

Methods: National TB control program of Afghanistan was reviewed in terms of its milestones, achievement parameters, and potential barriers. Information and data were collected by review visits to the Ministry of Health and health facility survey of non-governmental organizations working for TB control in Afghanistan.