Publications by authors named "Ibrahim M Fakhr"
Article Synopsis
- The study investigates pediatric germ cell tumors (GCTs) at a referral center over 8 years, focusing on the role of surgery and disease location in patient outcomes.
- A total of 34 children were analyzed, with an average age of 6.7 years; the majority were females, and common symptoms included abdominal swelling.
- Surgical intervention, either curative or for biopsy, was performed on all patients, with most receiving adjuvant chemotherapy; the results indicated better disease-free survival in those who underwent complete resection compared to those with irresectable tumors.
Background: Chronic HBV and HCV infections are the major risk factors for the development of HCC through a multistep pathway that involves viral and non-viral dependent pathophysiological steps. Hepatic expression of the nuclear proliferative marker ki-67 and the p53 oncoprotein were found to be associated with poor outcome. So, the present study was done to evaluate the changes in expression of Ki-67 and p53 oncoprotein, and to determine p53 gene mutation in HBV/HCV-related HCC Egyptian patients.
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