Micromonospora species from rarely-exploited Egyptian habitats: chemical profile, antimicrobial, and antitumor activities through antioxidant property.

The development of new anticancer agents with a selective action mechanism has become a significant scientific challenge, especially as cancers remain the world's leading cause of death. Actinobacteria and its bioactive compounds have recently become a promising perspective alternative to cancer therapy. In this study, some extracted metabolites of Micromonospora exhibited potent antimicrobial with microbial inhibition zone ≥ 7 mm, and cytotoxic activities against MCF-7 and HepG2 cell lines with promising activities ≥ 85%.

A panel of molecular markers in hepatitis C virus-related hepatocellular carcinoma.

Background: Hepatocellular carcinoma is triggered by many factors including infection with hepatitis C virus. The molecular basis, however, of the development of HCV-related HCC remains unknown.

Objective: This work was designated to compare the circulating levels of some molecular markers between HCV-infected and HCV-free HCC patients.