The Role of Serum HMGB-1 Level in Differentiating the Soft-Tissue Infection From Diabetic Foot Osteomyelitis.

Background: The incidence of diabetic foot infections is increasing due to the rising number of persons with diabetes and the prolonged life expectancy. It is vital to differentiate soft-tissue infection (STI) from diabetic foot osteomyelitis (DFO), as treatment modalities and durations vary widely, but this can be challenging. We aimed to assess the blood concentration levels of the high mobility group box 1 protein (HMGB-1) in STI and DFO compared to healthy subjects, and to investigate whether this protein could contribute to differentiating STI from DFO.

HMGB-1 Levels in Painful Knee Arthroplasty: Is it Possible to Distingue Periprosthetic Joint Infection and Aseptic Loosening?

Introduction: We investigated the efficiency of high mobility group box-1 protein (HMGB-1) in differentiation of asymptomatic knee prosthesis, and periprosthetic joint infection and aseptic loosening causing painful knee prosthesis.

Materials And Methods: The data of patients who consulted our clinic for checking after total knee arthroplasty surgery were recorded prospectively. Blood levels of CRP, ESR, WBC, and HMGB-1 were recorded.

Comparison of Clinical Outcomes of Endoscope-Assisted Technique and Conventional Surgery in Zone 2 Flexor Tendon Repair.

Purpose: The purpose of the study was to compare clinical outcomes between patients who underwent endoscope-assisted flexor tendon repair and those who underwent conventional surgery.

Methods: Patients were divided into 2 groups. Group 1 (endoscope-assisted surgery) included 21 patients (27 fingers) and group 2 (conventional surgery) included 19 patients (25 fingers).

Sitagliptin-induced Achilles enthesopathy: Case report and literature review.

Achilles enthesopathy is a pain caused due to inflammation of the insertion area of the Achilles tendon on the posterosuperior aspect of the calcaneus. Sometimes, isolated Achilles enthesopathy can be occurred, while, mostly, it is observed with rheumatological diseases. We herein aimed to report a case presentation, sitagliptin-induced enthesopathy, and literature review on musculoskeletal manifestations of gliptins.