chronic gastritis updated Sydney grading in relation to endoscopic findings and IgG antibody: diagnostic methods.

(Hp) inhabits the stomach of > 50% of humans and has been established as a major etiological factor in the pathogenesis of chronic gastritis, gastric atrophy, peptic ulcer disease, gastric adenocarcinoma, and gastric mucosa-associated lymphoid tissue lymphoma. The aim of this study was to provide unequivocal information about Hp-associated gastritis grading according to the Sydney grading system and to compare the histopathological features with the endoscopic findings and anti-Hp immunoglobulin (Ig)G serological status. This analytical study was conducted on 157 patients with dyspeptic gastritis.

The value of immunohistochemical expression of TTF-1, CK7 and CK20 in the diagnosis of primary and secondary lung carcinomas.

Objective: To study the value of immunohistochemical staining of thyroid transcription factor-1 TTF-1, cytokeratin 7 CK7, and cytokeratin 20 CK20 in the differentiation between primary and secondary pulmonary carcinomas.

Methods: Forty-three cases of lung carcinoma, 14 squamous cell carcinoma, 12 adenocarcinoma, 8 small cell carcinoma, 3 mesothelioma, and 6 metastatic tumors, were collected from the files of the Pathology Department, King Abdul-Aziz University Hospital, Jeddah, Saudi Arabia between 2004 and 2006. All cases were stained immunohistochemically following Avidin biotin method using monoclonal antibodies to TTF-1, CK7, and CK20.

Lupus nephritis. Clinicopathological correlation.

Objective: To classify all renal biopsies of lupus nephritis patients presenting in the last 10 years, according to the modified World Health Organization (WHO) classification using the facilities of light, fluorescent, and electron microscopy. To assess the activity and chronicity indices of renal biopsies according to the National Institute of Health protocol, and to correlate the histological findings with the clinical features of the patients presented up to the time of biopsy.

Methods: Seventy-eight patients with lupus nephritis, biopsied over 10 years between January 1995 to December 2005 in King Abdul-Aziz University Hospital, Jeddah, Kingdom of Saudi Arabia were reviewed by 2 histopathologists with the assistance of a nephrologist.

Colorectal cancers in Saudi Arabia.

Objective: The aim of this retrospective study is to delineate the histopathological profile of colorectal cancers seen at King AbdulAziz University Hospital, Jeddah, Kingdom of Saudi Arabia and to compare our findings with 12 other studies published in the literature from other areas of the Kingdom of Saudi Arabia.

Methods: Our study group consisted of 39 colorectal cancer patients, who were examined in the department of Histopathology at King AbdulAziz University Hospital, Jeddah, Kingdom of Saudi Arabia, over a period of 4 years from January 1996 to December 2000. The data was retrieved and analyzed.