Publications by authors named "Ibrahim H Tanboga"

Background: Heart failure (HF) remains a significant health problem despite advances in diagnosis and treatment options. Malnutrition and increased inflammation predict poor disease prognosis. The parameters of the Naples prognostic score (NPS) include albumin, total cholesterol, neutrophil-lymphocyte ratio (NLR), and lymphocyte-monocyte ratio (LMR).

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Objective: Controlling Nutritional Status score was previously described and has been used in predicting short- and long-term outcomes in different patient populations. The aim of this study was to test the relationship between Controlling Nutritional Status score and in-hospital mortality in coronary care unit patients (MORCOR-TURK population).

Methods: In this multicenter and national study, all patients with an available Controlling Nutritional Status score were included in the analysis.

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Article Synopsis
  • Coronary computed tomography angiography (CCTA) was evaluated as an alternative to intravascular imaging techniques for assessing plaque pathology in patients with chronic coronary syndrome.
  • The study involved 70 patients and compared CCTA with near-infrared spectroscopy-intravascular ultrasound (NIRS-IVUS) to analyze atheroma burden and composition, focusing on the accuracy of detecting lipid-rich plaques.
  • Results showed that CCTA had limitations in accurately measuring plaque dimensions and composition, leading to potential issues in planning for coronary interventions.
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Inflammatory prognostic index (IPI), has been shown to be related with poor outcomes in cancer patients. We aimed to investigate the predictive role of IPI for contrast-induced nephropathy (CIN) development in non-ST segment elevation myocardial infarction patients using a nomogram and performing machine learning (ML) algorithms. A total of 178 patients with CIN (+) and 1511 with CIN (-) were included.

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Objective: Pregnancy causes physiological, hormonal, and hemodynamic changes that affect the aortic wall dimensions and elastic properties. Multiple pregnancies increase the risk of aortic enlargement and reduce aortic elasticity. The aortic stiffness index (ASI) and aortic velocity propagation (AVP) are markers of elasticity.

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Background: Our primary goal was to utilize pulmonary arterial stiffness (PAS) to demonstrate the early alterations in the pulmonary vascular area in individuals with prior COVID-19 illness who had not undergone hospitalization.

Methods: In total, 201 patients with prior COVID-19 infection without hospitalization and 195 healthy, age- and sex-matched individuals without a history of COVID-19 disease were included in this prospective analysis. The PAS value for each patient was calculated by dividing the mean peak pulmonary flow velocity by the pulmonary flow acceleration time.

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Background: Currently available risk stratification models for acute pulmonary embolism (PE) include hemodynamic status, cardiac biomarkers, right ventricle (RV) dysfunction on imaging, and clinical scores. Focusing on the length-tension relationship of the ventricle might have a superior predictive capability over RV dysfunction in terms of mortality and classification of patients with acute PE. In this study, our hypothesis suggests that the tricuspid annular plane systolic excursion (TAPSE)/systolic pulmonary artery pressure (sPAP) ratio has superior predictive capability for in-hospital mortality in patients with acute PE compared to TAPSE or sPAP as distinct measures.

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Article Synopsis
  • - The study analyzed how calcific (Ca) burden affects the accuracy of coronary computed tomography angiography (CTA) in assessing plaque burden and composition, using near-infrared spectroscopy-intravascular ultrasound (NIRS-IVUS) as a comparison standard.
  • - Involving 64 patients and 186 vessels, results indicated that while Ca did not significantly alter correlations between NIRS-IVUS and CTA at the segment and lesion levels, it did affect their agreement at the cross-sectional level, specifically regarding lipid and Ca components.
  • - Ultimately, the presence of Ca burden influenced measurements and predictions of plaque volume and composition between NIRS-IVUS and CTA, highlighting the importance of considering coronary calcification in clinical evaluations.
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  • The study analyzed various immune and inflammatory indices to see how they predict in-hospital mortality in coronary care unit patients in Turkey, involving a large sample size of 3,157.
  • Out of these patients, 137 (4.3%) died during their hospital stay, with significant correlations found between mortality and several indices like the systemic immune-inflammatory index (SII), C-reactive protein/albumin ratio (CAR), neutrophil-lymphocyte ratio (NLR), and prognostic nutritional index (PNI).
  • Notably, when combining these indices, only the CAR significantly improved the predictive model for in-hospital mortality compared to the initial set of risk predictors.
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Background: Left ventricular hypertrophy (LVH), including hypertensive LVH, hypertrophic cardiomyopathy (HCM) and cardiac amyloidosis (CA), is a commonly encountered condition in cardiology practice, presenting challenges in differential diagnosis. In this study, we aimed to investigate the importance of echocardiographic evaluation of the inferior vena cava (IVC) in distinguishing LVH subtypes including hypertensive LVH, HCM, and CA.

Methods: In this retrospective study, patients with common causes of LVH including hypertensive LVH, HCM, and CA were included.

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Introduction: ST-segment elevation myocardial infarction (STEMI) represents the most harmful clinical manifestation of coronary artery disease. Risk assessment plays a beneficial role in determining both the treatment approach and the appropriate time for discharge. Hierarchical agglomerative clustering (HAC), a machine learning algorithm, is an innovative approach employed for the categorization of patients with comparable clinical and laboratory features.

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Purpose: The presence of right ventricular dysfunction indicates a higher risk status in patients with pulmonary embolism (PE). The RV strain evaluated by speckle-tracking echocardiography seems to be more reliable method in the evaluation of RV dysfunction as compared to standard echocardiographic measures. In this study, we aimed to determine the value of myocardial-work indices in evaluating serial changes of RV function in acute PE.

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Background: No-reflow (NR) is characterized by an acute reduction in coronary flow that is not accompanied by coronary spasm, thrombosis, or dissection. Inflammatory prognostic index (IPI) is a novel marker that was reported to have a prognostic role in cancer patients and is calculated by neutrophil/lymphocyte ratio (NLR) multiplied by C-reactive protein/albumin ratio.

Objective: We aimed to investigate the relationship between IPI and NR in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (pPCI).

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Background: AngioJet rheolytic thrombectomy (ART) system has been widely used as a catheter-directed treatment (CDT) method in acute pulmonary embolism (PE), however, there has been a controversy regarding the safety of its use. In this systematic review and meta-analysis, we evaluated the efficacy and safety outcomes of ART in patients with PE.

Methods: Our meta-analysis have been based on search in the MEDLINE, EMBASE, and Cochrane Library for studies published up to August 2022.

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Article Synopsis
  • The PRECISE-DAPT score, initially used to gauge bleeding risk in acute coronary syndrome (ACS) patients, can also help predict long-term mortality in those experiencing cardiogenic shock (CS).
  • A study involving 293 ACS patients found that higher PRECISE-DAPT scores were associated with an increased risk of all-cause mortality.
  • The findings suggest that the PRECISE-DAPT score could serve as a practical tool for assessing long-term survival risk in patients with ACS and CS.
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Background: Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia worldwide and is associated with an increased risk of thromboembolism, ischemic stroke, impaired quality of life, and mortality. The latest research that shows the prevalence and incidence of AF patients in Türkiye was the Turkish Adults' Heart Disease and Risk Factors study, which included 3,450 patients and collected data until 2006/07.The Turkish Real Life Atrial Fibrillation in Clinical Practice (TRAFFIC) study is planned to present current prevalence data, reveal the reflection of new treatment and risk approaches in our country, and develop new prediction models in terms of outcomes.

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Background: The optimal treatment of symptomatic paravalvular leak (PVL) remains controversial between transcatheter closure (TC) and surgery. This large-scale study aimed to retrospectively evaluate the long-term outcomes of the patients who underwent reoperation or TC of PVLs.

Methods And Results: A total of 335 (men, 209 [62.

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Article Synopsis
  • - The study compares the accuracy of automated coronary computed tomography angiography (CCTA) analysis with expert evaluations, using near-infrared spectroscopy-intravascular ultrasound imaging (NIRS-IVUS) as a standard for reference.
  • - In a test with 51 participants and 150 vessels, results indicated that both the expert and automated methods performed similarly at the segment level, but the experts were better at identifying specific lesions.
  • - Despite similarities in overall performance, both methods exhibited poor reliability in assessing certain metrics (like minimal lumen area), suggesting automated segmentation can still speed up CCTA analysis in clinical settings.
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  • The Naples prognostic score (NPS) is an established scoring system that assesses inflammation and nutrition, but its impact on in-hospital mortality in STEMI patients was previously unexamined.
  • A study involving 3,828 STEMI patients showed that higher NPS scores were linked to increased rates of in-hospital mortality, even after adjusting for various health factors.
  • The findings suggest that NPS might be a useful predictor of in-hospital mortality in STEMI cases, warranting further research to solidify its clinical application.
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Current guidelines recommend individualizing the choice and duration of P2Y inhibitor therapy based on the trade-off between bleeding and ischemic risk. However, whether a potent P2Y inhibitor (ticagrelor) or a less potent one (clopidogrel) is more appropriate in patients with acute coronary syndrome (ACS) in the setting of high bleeding or ischemic risk is not clear. The study aimed to compare the clinical outcomes of clopidogrel and ticagrelor in patients with ACS at high bleeding or ischemic risk.

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  • The study focuses on how pulmonary artery (PA) enlargement in patients with severe pulmonary hypertension (PH) can indicate potential complications like left main coronary artery compression (LMCA-Co) and Ortner syndrome, which causes hoarseness.
  • Researchers analyzed data from 865 PH patients who underwent tests to assess these complications and evaluated the correlation between PA size and clinical symptoms.
  • Results showed that larger PA diameters were strongly linked to both LMCA-Co and hoarseness, suggesting that monitoring PA size could help predict these serious issues in patients with PH.
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  • The study investigated how well ECG readings can predict pulmonary hemodynamics using right heart catheterization data from 562 patients over 16 years.
  • Significant correlations were found between specific ECG measures (like P-wave amplitude and R/S ratio) and pulmonary pressures and resistance, while some measures did not correlate.
  • Key ECG indicators effectively predicted pulmonary hypertension and precapillary hypertension, suggesting that certain ECG metrics could be useful for early identification of these conditions.
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