A Hybrid Deep Learning Model with Data Augmentation to Improve Tumor Classification Using MRI Images.

Background: Cancer ranks second among the causes of mortality worldwide, following cardiovascular diseases. Brain cancer, in particular, has the lowest survival rate of any form of cancer. Brain tumors vary in their morphology, texture, and location, which determine their classification.

Ecological features of microbial community linked to stochastic and deterministic assembly processes in acid mine drainage.

Unlabelled: Ecological processes greatly shape microbial community assembly, but the driving factors remain unclear. Here, we compiled a metagenomic data set of microbial communities from global acid mine drainage (AMD) and explored the ecological features of microbial community linked to stochastic and deterministic processes from the perspective of species niche position, interaction patterns, gene functions, and viral infection. Our results showed that dispersal limitation (DL) (48.

Exploring the linkages between social media use, self-esteem, and academic performance among nursing students in Saudi Arabia: A descriptive correlational study.

Background: The prevalence of social media influence in education makes it necessary to investigate how it might affect nursing students' academic achievement and sense of self. To our knowledge, the associations between academic performance, self-esteem, and social media usage among nursing students from Saudi Arabia remain understudied.

Objective: This study aimed to examine the relationships between academic performance, self-esteem, and the utilization of social media platforms by Saudi Arabian nursing students.

Evaluating the Effect of TeamSTEPPS on Teamwork Perceptions and Patient Safety Culture among Newly Graduated Nurses.

Background: Quality healthcare delivery is contingent upon effective teamwork and a patient safety-focused culture. TeamSTEPPS offers an evidence-based framework that enhances these competencies. However, the impact of TeamSTEPPS on newly graduated nurses, who undergo a significant transitional phase, has yet to be comprehensively explored.

Synergistic Differential DNA Demethylation Activity of () Associated with Different Probiotics in Nonalcoholic Fatty Liver Disease.

Nonalcoholic fatty liver disease (NAFLD) is a major hepatic disorder occurring in non-alcohol-drinking individuals. Salvianic acid A or (DSS, 3-(3, 4-dihydroxyphenyl)-(2)-lactic acid), derived from the root of (), has demonstrated heart and liver protective properties. In this work, we investigated the antioxidant activity and hepatoprotective activity of alone and in combination with different agents, such as probiotic bacteria ( and ), against several assays.

Amelioration effect of 18β-Glycyrrhetinic acid on methylation inhibitors in hepatocarcinogenesis -induced by diethylnitrosamine.

Aim: suppression of methylation inhibitors (epigenetic genes) in hepatocarcinogenesis induced by diethylnitrosamine using glycyrrhetinic acid.

Method: In the current work, we investigated the effect of sole GA combined with different agents such as doxorubicin (DOX) or probiotic bacteria () against hepatocarcinogenesis induced by diethylnitrosamine to improve efficiency. The genomic DNA was isolated from rats' liver tissues to evaluate either methylation-sensitive or methylation-dependent resection enzymes.

Quercetin mitigates doxorubicin-induced neurodegenerative changes in the cerebral cortex and hippocampus of rats; insights to DNA damage, inflammation, synaptic plasticity.

Background: Doxorubicin (Dox) is one of the most effective anti-neoplastic agents. Quercetin (QE) exhibits antioxidant and anti-inflammatory properties.

Aim: To detect neuroprotective properties of quercetin in rats exposed to doxorubicin-induced brain injury.

Peri-anal infiltration versus caudal block for multimodal analgesia in paediatric patients with Hirschsprung's disease undergoing transanal endorectal pull-through procedure: A randomised trial.

Background And Aims: Transanal endorectal pull-through (TERPT) is a standard procedure for managing paediatric patients with Hirschsprung's disease (HD). This study aimed to evaluate peri-anal infiltration versus caudal block as a part of multimodal analgesia for paediatric patients with HD undergoing the TERPT procedure.

Methods: This randomised trial included 60 patients of both genders, aged 6 to 18 months who underwent the TERPT procedure under general anaesthesia.

Symbiotic Antidiabetic Effect of Lactobacillus casei and the Bioactive Extract of Cleome droserifolia (Forssk.) Del. on Mice with Type 2 Diabetes Induced by Alloxan.

The consumption of probiotics protects pancreatic β-cells from oxidative damage, delaying the onset of type 2 diabetes mellitus (T2DM) and preventing microvascular and macrovascular complications. This study aimed to evaluate the antidiabetic activity of CDE fermented by Lactobacillus casei (ATCC 39539) (LC) in alloxan-induced diabetic rats. The oxidative stress identified by catalase (CAT), serum AST, ALT, ALP, creatinine, urea, and uric acid were measured.

Expression of Concern: Solid-state dye-sensitized solar cells based on ZnSnO nanocomposite photoanodes.

Expression of Concern for 'Solid-state dye-sensitized solar cells based on ZnSnO nanocomposite photoanodes' by Ayat Nasr El-Shazly , , 2018,, 24059-24067, DOI: https://doi.org/10.1039/c8ra02852d.

AI-driven Discovery of Celecoxib and Dexamethasone for Exploring their Mode of Action as Human Interleukin (IL-6) Inhibitors to Treat COVID-19-induced Cytokine Storm in Humans.

Background: In the case of COVID-19 patients, it has been observed that the immune system of the infected person exhibits an extreme inflammatory response known as cytokine release syndrome (CRS) where the inflammatory cytokines are swiftly produced in quite large amounts in response to infective stimuli. Numerous case studies of COVID-19 patients with severe symptoms have documented the presence of higher plasma concentrations of human interleukin-6 (IL-6), which suggests that IL-6 is a crucial factor in the pathophysiology of the disease. In order to prevent CRS in COVID-19 patients, the drugs that can exhibit binding interactions with IL-6 and block the signaling pathways to decrease the IL-6 activity may be repurposed.

The role of professional identity and job satisfaction in paediatric nurses' intention to remain employed amidst the COVID-19 pandemic.

The COVID-19 pandemic has significantly affected nursing, as nurses are crucial in providing healthcare services. Understanding the factors influencing nurse retention is essential for maintaining a strong and long-lasting workforce because nurse retention is becoming increasingly complex. This study aimed to investigate the influence of professional identity and job satisfaction on the intention to remain employed while also evaluating the levels of professional identity, job satisfaction, and intention to stay among paediatric nurses amidst the COVID-19 pandemic.

Perforated gallbladder in neonates with review of literature.

Introduction: Neonatal perforated gallbladder is a rare and implausible surgical emergency. Pneumoperitonium and neonatal intestinal obstruction are the main clinical presentations. Many cases of neonatal perforated gallbladder had no clear pathology.

An efficient multilevel image thresholding method based on improved heap-based optimizer.

Image segmentation is the process of separating pixels of an image into multiple classes, enabling the analysis of objects in the image. Multilevel thresholding (MTH) is a method used to perform this task, and the problem is to obtain an optimal threshold that properly segments each image. Methods such as the Kapur entropy or the Otsu method, which can be used as objective functions to determine the optimal threshold, are efficient in determining the best threshold for bi-level thresholding; however, they are not effective for MTH due to their high computational cost.

An Improved Search and Rescue Algorithm for Global Optimization and Blood Cell Image Segmentation.

Image segmentation has been one of the most active research areas in the last decade. The traditional multi-level thresholding techniques are effective for bi-level thresholding because of their resilience, simplicity, accuracy, and low convergence time, but these traditional techniques are not effective in determining the optimal multi-level thresholding for image segmentation. Therefore, an efficient version of the search and rescue optimization algorithm (SAR) based on opposition-based learning (OBL) is proposed in this paper to segment blood-cell images and solve problems of multi-level thresholding.

Rectovestibular fistula: Which surgical approach is suitable? A randomized controlled trial.

The management of a vestibular fistula is a challenge for pediatric surgeons. We compared four different operative techniques in terms of postoperative complications, continence, and cosmetic appearance. This prospective, randomized, comparative study included female children with rectovestibular fistulae who were selected from patients with Anorectal Malformations (ARMs) treated between January 2016 and July 2020.

Chlorella vulgaris or Spirulina platensis mitigate lead acetate-induced testicular oxidative stress and apoptosis with regard to androgen receptor expression in rats.

The current research was constructed to throw the light on the protective possibility of Chlorella vulgaris (C. vulgaris) and Spirulina platensis (S. platensis) against lead acetate-promoted testicular dysfunction in male rats.

Conjoined twins: A report of four cases.

Background: Conjoined twin is a rarely seen congenital anomaly associated with significant morbidity and mortality. The most common types of conjoined twins are thoracopagus. Conjoined twins are either symmetrical twins or asymmetrical or heteropagus.

Awareness of medical students toward forensic medicine at Albaha University medical college, Saudi Arabia.

Awareness of medical students towards forensic medicinewas assessed at Albaha University, Saudi Arabia in 2016. This report aimed to provide detail descriptive and analytical findings of the cross-sectional survey conducted to explore the medical students' awareness towards forensic medicine and the factors affecting their choice of this specialty in the future. It was found that more than half of the students (63.

The Significance of Buffer Solutions on Corrosion Processes of Cobalt Ferrite CoFeO Thin Film on Different Substrates.

Background: The spinel ferrite nanoparticles, such as zinc, nickel, and cobalt ferrites have exceptional electronic and magnetic properties. Cobalt ferrite nanomaterial (CoFe2O4) is a hard material that reveals high magnetic, mechanical, and chemical stability.

Aim And Objective: The objective of this research is to predict the corrosion behavior of cobalt ferrite (CoFe2O4) thin films deposited on different substrates (platinum Pt, stainless steel S.

A Novel Approach for Classifying Native Chinese and Malay Speaking Persons According to Cortical Auditory Evoked Responses.

Objectives: This study uses a new approach for classifying the human ethnicity according to the auditory brain responses (electroencephalography [EEG] signals) with a high level of accuracy. Moreover, the study presents three different algorithms used to classify the human ethnicity using auditory brain responses. The algorithms were tested on Malays and Chinese as a case study.

The effects of audio stimuli on auditory-evoked potential in normal hearing Malay adults.

Objectives: The hearing process in the brain is very complicated and hard to solve. However, an understanding of the hearing process is an essential issue and needed in many rehabilitation or treatment applications. This study investigates and compares the effects of simple and complex sounds on latency and amplitude of various event-related potential (ERP) components to male ethnic Malay adults.

Response Surface Methodology for Optimization of Genistein Content in Soy Flour and its Effect on the Antioxidant Activity.

Biotransformation of isoflavones glycosides into the aglycone form is essential to attain the maximum bioavailability. The factors affecting deglycosylation of genistin in soy flour using commercial -glucosidase enzyme were evaluated. The presence of genistin in soy flour was confirmed by isolation through chromatographic fractionation and identification by spectral method.

Solid-state dye-sensitized solar cells based on Zn Sn O nanocomposite photoanodes.

Solid-state dye-sensitized solar cells (ss-DSSCs) comprising Sn-substituted ZnO nanopowder were purposefully tailored a co-precipitation method. The solar cells assembled in this work were sensitized with N719 ruthenium dye and insinuated with spiro-OMeTAD as a solid hole transport layer (HTL). Evidently, significant enhancement in cell efficiency was accomplished with Sn ions-substituted ZnO photoelectrodes by maintaining the weight ratio of SnO at 5%.