Publications by authors named "Ibraheem I Abdelaal"
Background: Preterm prelabor rupture of membranes is associated with polymicrobial infection; hence broad-spectrum antibiotics are recommended. Nowadays, Azithromycin is used instead of Erythromycin due to erythromycin shortages, its ease of administration, decreased cost, and better side effect profile. This study aimed to evaluate the efficacy of different azithromycin protocols for the conservative management of preterm prelabor rupture of membranes.
View Article and Find Full Text PDFObjectives: To evaluate tissue concentration of 1, 25 dihydroxyvitamin D3, and gene expression level of CYP27B1 that codes for 1-α hydroxylase (vitamin D activating enzyme), and CYP24A1 that codes for 24-hydroxylase (vitamin D catabolizing enzyme) in human uterine leiomyoma (ULM), its adjacent myometrium (Myo-F), and normal myometrium (Myo-N).
Study Design: Levels of 1, 25 dihydroxyvitamin D3 were measured using HPLC and Diode detectors whereas CYP27B1, and CYP24A1 expressions were assessed using Real-Time PCR in ULM, Myo-F, and Myo-N. Non-parametric statistics were used.
Article Synopsis
- Telocytes are specialized cells found in human uterine leiomyoma (ULM) and adjacent tissues, and they were characterized using advanced techniques like immunohistochemistry and electron microscopy.
- Higher numbers of telocytes were identified in ULM compared to adjacent myometrium tissues (Myo-F) and normal myometrium (Myo-N), indicating their increased cellular activity.
- Telocytes in ULM may play crucial roles in hormone sensing, supporting myocyte formation, and regulating signaling pathways, highlighting their importance in uterine health.
Soluble tumor necrosis factor-alpha receptors in the serum of endometriosis patients.
Eur J Obstet Gynecol Reprod Biol
May 2016
Introduction: We examine serum levels sTNFR-I and sTNFR-II in endometriosis patients, and their role as biomarkers of endometriosis.
Material And Methods: Women were diagnosed with endometriosis during laparoscopy to investigate pelvic pain and/or infertility (N=62). Control group included women with pelvic pain and/or infertility, whose laparoscopy showed no abnormalities (N=55).
Objective: Our aim was to screen a panel of modified adenoviral gene transfer vectors to identify those which can sustain high gene expression in human endometrial cells.
Methods: Normal endometrial stromal cell cultures were established from endometrial lining of hysterectomy specimens performed for benign gynecologic indications. Human endometrial stromal cells were transfected by modified adenoviruses expressing luciferase reporter gene.