Publications by authors named "Ibidayo Sangowawa"
Res Pract Thromb Haemost
July 2023
Article Synopsis
- - This study investigates the role of platelet factor XIII-A (FXIII-A) in enhancing platelet function and activation during blood clotting, highlighting its significance beyond traditional antifibrinolytic roles.
- - The research uses normal platelets and FXIII-deficient platelets to analyze how FXIII-A affects fibrinogen binding, platelet aggregation, and clot retraction in blood samples, revealing that FXIII-A is critical for optimal platelet response to stimuli.
- - Findings indicate that the absence of FXIII-A diminishes platelet activation and spreading, leading to weaker clot formation and retraction, emphasizing the enzyme's essential contribution to effective thrombus formation.
