Publications by authors named "Iben B Damgaard"
Purpose: To evaluate the 7-year visual, refractive, and optical outcomes following small incision lenticule extraction (SMILE) for high myopia and myopic astigmatism.
Methods: Sixty-nine eyes (69 patients) undergoing SMILE between March 2011 and January 2012 at Aarhus University Hospital were included. Preoperative, 3-month, 3-year, and 7-year evaluation included: manifest refraction and uncorrected (UDVA) and corrected (CDVA) distance visual acuities, total corneal refractive power (TCRP), average keratometry (Km), aberrations, and central corneal thickness (CCT).
Purpose: To evaluate the feasibility of intrastromal lenticule rotation (ISLR) as a novel technique for management of astigmatism up to 10.00 diopters (D).
Methods: Eighteen human donor corneas were mounted on an artificial anterior chamber.
Purpose: To compare centration and functional optical zone (FOZ) after small incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis (LASIK).
Methods: In this prospective, randomized, single-masked, paired-eyed, clinical trial, 70 patients received SMILE in one eye and LASIK in the other eye for myopia and myopic astigmatism. FOZ was calculated using custom software on 3-month postoperative refractive power maps (Pentacam HR; Oculus Optikgeräte GmbH, Wetzlar, Germany).
Implantation of biological corneal inlays, derived from small incision lenticule extraction, may be a feasible method for surgical management of refractive and corneal diseases. However, the refractive outcome is dependent on stromal remodelling of both the inlay and recipient stroma. This study aimed to investigate the refractive changes and tissue responses following implantation of 2.
View Article and Find Full Text PDFWorldwide, femtosecond Laser Assisted Keratomileusis (LASIK) is a well known and commonly used refractive technique, although Small Incision Lenticule Extraction (SMILE) has become increasingly popular since it was introduced in 2011. In LASIK, a corneal flap is cut with a microkeratome or femtosecond laser, followed by thinning of the stromal bed with excimer laser ablation. In SMILE, a minor intrastromal lenticule is cut with a femtosecond laser and subsequently removed through a small incision, leaving the anterior and strongest part of the cornea almost intact.
View Article and Find Full Text PDFPurpose: To evaluate the feasibility of excimer laser reshaping of biological lenticules available after small incision lenticule extraction (SMILE).
Methods: Fresh and cryopreserved SMILE-derived human lenticules underwent excimer laser ablation for stromal reshaping. The treatment effects in the lasered group were compared with the nonlasered group with respect to changes in surface functional groups (by Fourier transform infrared spectroscopy [FTIR]) and surface morphology (by scanning electron microscopy [SEM] and atomic force microscopy [AFM]).
Purpose: To evaluate changes in corneal tomography after stromal lenticule implantation ex vivo, with respect to the dependency of the lenticule thickness and implantation depth on the corneal curvature and the postoperative biomechanical strength at increased chamber pressure.
Methods: Twenty-eight human donor corneas underwent pocket implantation of refractive stromal lenticules. Four groups were created by the combination of two implantation depths (110 and 160 µm) and two lenticule thicknesses (95 µm = 4.
Purpose: To examine the refractive correction and corneal biomechanical strength after small incision lenticule extraction (SMILE) by using a 110- or 160-μm cap thickness.
Methods: Thirty-two human donor corneas were allocated into 4 groups, combining one of two cap thicknesses (110 and 160 μm) with one of two spherical corrections (-4 D and -8 D). Each cornea was mounted on an artificial anterior chamber.
Purpose: To compare intraoperative and postoperative subjective patient experience after small incision lenticule extraction (SMILE) and femtosecond laser-assisted LASIK.
Methods: In a prospective, randomized, paired-eye, single-masked clinical trial at Singapore National Eye Centre, 70 patients were randomly treated with SMILE and LASIK in each eye. The intraoperative questionnaire was completed immediately after surgery and included light perception and levels of anxiety, fear, and discomfort.