[Kinin-modifying therapy of patients with myocardial infarction].

According to clinical characteristics and serum levels of alpha 1-proteinase inhibitor in the acute period (1-3 days), four groups of patients with myocardial infarction were identified. The most severe myocardial infarction was observed in patients from Groups 1 and 4. It was found that the serum alpha 1-proteinase inhibitor ratios in acute myocardial infarction were closely related to its clinical course.

[The kinin and blood coagulation systems in patients with myocardial infarction during rehabilitation].

In 161 patients with acute myocardial infarction, the kallikrein-kinin system was found to be activated. In addition, there were alterations in indices of the coagulative system, which were suggestive of hypercoagulation. The unidirectional changes in the indices of the systems in question during therapy in the periods of rehabilitation are attributable to the common character of trigger mechanisms responsible for their activation and to the involvement of the kinin system in the regulation of hemostatic potential.

[Various indices of the kallikrein-kinin and clotting systems of the blood of patients with acute myocardial infarcts with and without essential hypertension].

The kinin and coagulation functions were examined in 78 myocardial infarction patients in relation to the presence of essential hypertension. The kallikrein-kinin activation and blood hypercoagulation were shown to be more pronounced in cases of associated essential hypertension.