Publications by authors named "Ianushkene T"

Article Synopsis
  • The thrombocyte membranes' ability to bind Ca(2+) remains unchanged initially after hydrocortisone administration, with no significant effect on arterial pressure observed.
  • In cases of sustained increased arterial pressure due to repeated hydrocortisone doses, intracellular Ca2+ levels shift, decreasing at the outer membrane and increasing within the cell.
  • This redistribution of Ca2+ may be related to hypertension mechanisms seen in both essential and steroid-induced forms, possibly involving the cell's adrenoreceptor mechanisms.
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High contents of Ca2+ was revealed in thrombocytes' intracellular compartments in patients with essential hypertension. In response to different stimuli, large amount of Ca2+ can be released in the platelets of the patients which makes a considerable contribution to generation of the Ca2+ signal and activation of thrombocytes in cardiovascular diseases.

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The investigation was aimed at analyzing membrane-bound calcium in platelets of patients with essential hypertension (EH) and of healthy persons. 55 men were examined. Of these, 38 presented with EH and 17 were healthy.

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The combination of interventricular artery ligation and extracorporeal intensive ultraviolet irradiation of autoblood enabled the researchers to bring down the threshold and to increase the frequency of ventricular fibrillations. The above finding has served as a basis for creating a new experimental model of delayed ventricular fibrillation with a higher possibility of its development.

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A group of 242 males, aged 35 to 45 years, employed as engineers in several research institutions, was examined. The examination was conducted in accordance with WHO recommendations. Among the biochemical indices the blood level of lipids (cholesterol, triglycerides) and the lipoprotein spectrum of the blood serum were determined by means of polyacrylamide gel electrophoresis.

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Diurnal fluctuations in the level of cholesterol, phospholipids, triglycerides, NEFA and sugar in the blood of practically healthy subjects and in patients with ischemic heart disease, attended by hyperlipoproteinemia of the II and IV types, were studied. Investigations were made at 9 a.m.

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