Publications by authors named "Ian Mugisa"
Background: Tuberculosis (TB) continues to persist with a high disease burden globally. Non-adherence to treatment remains a major problem to TB control. In Uganda, one in every four TB patients does not adhere to their TB medication.
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- - Clinical vaccine development follows a linear process through Phases 1 to 4, focusing on safety and efficacy, but candidate vaccines for certain filoviruses face extended timelines due to lack of identified correlates of protection.
- - The Sabin Vaccine Institute sought alternatives for faster licensure of Marburg and Ebola Sudan virus vaccines in a May 2021 meeting, considering an "animal rule-like" approach due to the urgent need and limited treatment options for these diseases.
- - Discussion centered on regulatory strategies within Uganda, which has ongoing Ebola vaccine trials, and the potential for licensure through the well-established processes of the U.S. FDA.