Delayed Presentation of Bowel Injury Associated with Pelvic Fragility Fracture in Patient with Bladder Sling: A Case Report.

Case: An 85-year-old woman with a history of bladder mesh sling placement sustained a pelvic fracture and extraperitoneal bladder rupture after a ground-level fall. The patient underwent cystorrhaphy and percutaneous anterior column screw placement. Free air was identified on abdominal computed tomography scan on postoperative day 5.

Proximal Femur Peri-Implant Fracture After Lateral Femur Locking Plate: A Report of 2 Cases.

Case: This case report discusses 2 cases of proximal femur peri-implant fractures after the use of lateral locking plates for distal femur periprosthetic fractures.

Conclusion: The use of locking plate technology for fixation of distal femur periprosthetic fractures is a common treatment modality. Although much has been reported regarding healing and complication rates of distal femoral periprosthetic fractures, little has been reported about peri-implant fractures subsequent to treatment using locking plates.

Cefazolin Monotherapy Versus Cefazolin Plus Aminoglycosides for Antimicrobial Prophylaxis of Type III Open Fractures.

Background: There are conflicting recommendations between organizations regarding aminoglycoside use for the prophylaxis of type III open fractures.

Study Question: To compare cefazolin monotherapy versus cefazolin plus aminoglycoside therapy for prophylaxis of type III open fractures in trauma patients.

Study Design: This was a multicenter, retrospective, cohort study conducted in 3 academic medical centers in the United States.

Programmable protein arrays for immunoprofiling HPV-associated cancers.

Over 600,000 cancers each year are attributed to the human papillomavirus (HPV), including cervical, anogenital and oropharyngeal cancers (OPC). A key challenge in understanding HPV immunobiology is the diversity of oncogenic HPV types and the need for multiplexed display of HPV antigens to measure antibody responses. We have generated custom HPV protein microarrays displaying 98 proteins as C-terminal GST fusion proteins, representing eight antigens of two low-risk HPV types (HPV6 and 11) and ten oncogenic high-risk HPV types (HPV16, 18, 31, 33, 35, 39, 45, 51, 52 and 58).