Publications by authors named "Ian Heck"
The real-time monitoring of neurochemical release plays a critical role in understanding the biochemical process of the complex nervous system. Current technologies for such applications, including microdialysis and fast-scan cyclic voltammetry, suffer from limited spatiotemporal resolution or poor selectivity. Here, we report a soft implantable aptamer-graphene microtransistor probe for real-time monitoring of neurochemical release.
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- Extensive research shows that high molecular weight neurochemicals, like neuropeptides, are crucial in various neurological disorders, but current detection methods are limited in small animal models.
- A new wireless push-pull microsystem allows for membrane-free neurochemical sampling with cellular spatial resolution in freely moving animals, demonstrating high recovery rates.
- This innovative device does not hinder natural mouse behavior and enables the capture of neuropeptide Y release, opening new avenues for studying neurochemical impacts on behavior.