Synchronicity of the Gulf Stream path downstream of Cape Hatteras and the region of maximum wind stress curl.

The Gulf Stream, a major ocean current in the North Atlantic ocean is a key component in the global redistribution of heat and is important for marine ecosystems. Based on 27 years (1993-2019) of wind reanalysis and satellite altimetry measurements, we present observational evidence that the path of this freely meandering jet after its separation from the continental slope at Cape Hatteras, aligns with the region of maximum cyclonic vorticity of the wind stress field known as the positive vorticity pool. This synchronicity between the wind stress curl maximum region and the Gulf Stream path is observed at multiple time-scales ranging from months to decades, spanning a distance of 1500 km between 70 and 55W.

Liposome-based delivery of a boron-containing cholesteryl ester for high-LET particle-induced damage of prostate cancer cells: a boron neutron capture therapy study.

Purpose: The efficacy of a boron-containing cholesteryl ester compound (BCH) as a boron neutron capture therapy (BNCT) agent for the targeted irradiation of PC-3 human prostate cancer cells was examined.

Materials And Methods: Liposome-based delivery of BCH was quantified with inductively coupled plasma-mass spectrometry (ICP-MS) and high-performance liquid chromatography (HPLC). Cytotoxicity of the BCH-containing liposomes was evaluated with neutral red, 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS), and lactate dehydrogenase assays.

Experimental validation of the new nanodosimetry-based cell survival model for mixed neutron and gamma-ray irradiation.

The new nanodosimetry-based linear-quadratic (LQ) formula has been reviewed for mixed-LET irradiation. V-79 Chinese hamster cells have been irradiated with a mixed-LET field of fission neutrons and gamma rays at the University of Maryland Training Reactor (MUTR). The results show that the experimental survival curve agrees well with that predicted by the new nanodosimetry-based LQ model.