Publications by authors named "Ian Edward Smith"
Comparison of mathematically arterialised venous blood gas sampling with arterial, capillary, and venous sampling in adult patients with hypercapnic respiratory failure: a single-centre longitudinal cohort study.
BMJ Open Respir Res
June 2023
Article Synopsis
- Accurate arterial blood gas (ABG) analysis is critical for managing hypercapnic respiratory failure, but the process can be painful and often leads to missed samples, affecting patient care.
- A new method called v-TAC, which uses a venous blood sample and mathematical models, shows promise as a less invasive alternative to traditional ABG sampling for specific patient groups.
- In a study comparing v-TAC with ABG, capillary, and venous sampling, v-TAC demonstrated high accuracy and was less painful, suggesting it could effectively replace routine ABG testing.
Recent randomised controlled trials suggest non-invasive ventilation may offer benefit in the long-term management of ventilatory failure in stable COPD. The best mode of ventilation is unknown and newer volume assured modes may offer advantages by optimising ventilation overnight when treatment is delivered. This study compares volume assured with pressure preset non-invasive ventilation.
View Article and Find Full Text PDFPatients with ventilatory failure due to chronic obstructive pulmonary disease (COPD) are increasingly managed with long-term non-invasive positive pressure ventilation (NIPPV) and this may improve survival. NIPPV can frequently be interrupted but there are few data detailing the short-term effects and none on the longer-term consequences of treatment withdrawal. Ten patients withdrew from NIPPV for 1 week and were randomised to restart NIPPV or to continued withdrawal for up to 6 months.
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