An Outbreak of Pseudomonas Aeruginosa Infection Linked to a "Black Friday" Piercing Event.

Introduction: Outbreaks linked to cosmetic piercing are rare, but can cause significant illness. We report the investigation and management of a point-source outbreak that occurred during a Black Friday promotional event in North West England.

Methods: Outbreak investigation was led by Public Health England, and included active case finding among individuals pierced at a piercing premises between 25/11/2016 (Black Friday) and 7/12/2016.

Sex-Specific Effects of Stress on Oxytocin Neurons Correspond With Responses to Intranasal Oxytocin.

Background: Oxytocin (OT) is considered to be a stress-buffering hormone, dampening the physiologic effects of stress. However, OT can also be anxiogenic. We examined acute and long-lasting effects of social defeat on OT neurons in male and female California mice.

Effects of social defeat on dopamine neurons in the ventral tegmental area in male and female California mice.

Dopamine neurons in the ventral tegmental area (VTA) have important functions related to rewards but are also activated in aversive contexts. Electrophysiology studies suggest that the degree to which VTA dopamine neurons respond to noxious stimuli is topographically organized across the dorsal-ventral extent. We used c-fos immunohistochemistry to examine the responses of VTA dopamine neurons in contexts of social defeat and social approach.

Effects of kappa opioid receptors on conditioned place aversion and social interaction in males and females.

The effects of kappa opioid receptors (KOR) on motivated behavior are well established based on studies in male rodents, but relatively little is known about the effects of KOR in females. We examined the effects of KOR activation on conditioned place aversion and social interaction in the California mouse (Peromyscus californicus). Important differences were observed in long-term (place aversion) and short-term (social interaction) effects.

A review of controlled substances.

Physicians who understand the Controlled Substances Act and their regulations will have fewer complications and problems. The tracking/monitoring system helps protect physicians and their patients from problems with abuse and diversion. The understanding that pharmacists are utilizing their skills everyday in reviewing a patient's pharmaceutical history and aiding the patient will no doubt encourage increased interaction among the healthcare fields and increase the quality of treatment for the patient.