Platelet storage in more than 90% additive solution containing glucose and bicarbonate has the potential to increase shelf life.

Background: Platelet concentrates (PCs) suspended in more than 90% additive solution (AS) are recommended for patients with reactions to platelets stored in plasma. Next-generation AS containing glucose and bicarbonate might enable storage of these PCs for longer than those in current-generation AS, which was therefore evaluated in this study.

Study Design And Methods: Five buffy coat or apheresis-derived PCs were pooled and split into identical units.