Publications by authors named "Ian Breakspear"

The 2018 Declaration of Astana identifies traditional knowledge (TK) as one of the drivers for strengthening primary health care systems through the use of technology (traditional medicines) and knowledge and capacity building (traditional practitioners). While TK underpins both traditional practice and the use of traditional medicines, facilitating the use of TK in contemporary health care systems has been difficult to achieve. The aim of this study was to identify key factors related to the translation of TK into contemporary settings to help establish tools to support the knowledge translation process.

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Background: Clinical guidelines recommend non-pharmacological interventions as the first line of treatment for agitation in dementia. One intervention that shows some promise as a treatment for agitation is essential oils. The objective of this study was to provide preliminary evidence of the effectiveness and feasibility of using topically-administered, individualized essential oil preparations for the alleviation of agitation in persons with dementia.

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Olive leaf extract (OLE), prepared from the fresh or dried leaves of L., is generating interest as a cardiovascular and metabolic disease risk modifier. Positive effects for the leaf extract and its key phytochemical constituents have been reported on blood pressure, respiratory infections, inflammation, and insulin resistance.

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Article Synopsis
  • Comfrey, coltsfoot, and borage have been traditionally used for their therapeutic properties, but concerns about their safety stem from the presence of potentially harmful unsaturated pyrrolizidine alkaloids (PAs).
  • A systematic review was conducted on case reports concerning health issues related to the ingestion of these herbs to evaluate their reliability for safety assessments.
  • The review found 11 suitable reports, with nine showing possible associations between the herbs and adverse effects; however, inconsistencies in species identification raised doubts about the validity of these reports, indicating that better toxicological studies are needed for accurate risk assessment.
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