[Method for study of phase transitions in evaporating drop and its application for evaluation of physical-chemical properties of water and water solutions].

Spatial-temporal crystallization features of inorganic chlorides in evaporating drops of water solutions, considering solid surface wettability, were studied using a microscopic technique and the acoustical impedansometry. Physical-chemical mechanisms responsible for the difference in "dynamical portraits" of distilled water and salt solutions, as well as relaxation effects in water were discussed. The study demonstrated the potential use of a drying drop method in registration of changes in water properties under the action of physical and chemical factors.

[Dynamics of the mechanical properties of drops of biological liquids during drying as a reflection of the features of selfassembly of their components from the nano- to microlevel].

It has been shown that the dynamics of the molecular self-assembly of the components of liquids drying in the form of drops on a solid moistened surface contains information about their composition and structure. The physical mechanisms of this phenomenon have been considered. A method of recording this dynamics and retrieving useful information has been suggested.

[Shaping processes in drying drops of serum in norm and pathology].

The results of physical and mathematical simulation of the drying process for colloid liquids under different initial conditions were considered. It was shown that the concentration and stability of a colloid solution play an important role in the shaping of drying drops. Possible mechanisms of the formation of morphological differences in dried drops of serum in healthy and ill people are discussed.

[Changes in dynamics of phase transitions in various liquids by recording of acoustic mechanical impedance of a drying drop].

A method of studying multicomponent liquids is proposed, which is based on recording the dynamics of the acoustomechanical impedance of a drop that dries up on the surface of a quartz resonator oscillating with an ultrasound frequency. The magnitude of the acoustomechanical impedance is an integral characteristic of the physical properties of the drop such as viscosity, composition, surface tension, moistening, and inner structure. Using liquids of different types as an example, it was shown that each liquid possesses its individual "portrait", which is determined by the phase transitions.

[Bile crystallography and viscosimetry in cholelithiasis].

High prevalence of cholelithiasis necessitates development of an easy screening diagnostic method, and therefore structural analysis of a dried drop of biological fluid attracts special attention. A new method, clinical crystallography, has been used for analysis of bile from patients with cholelithiasis. A relationship between the crystal morphology and biological fluid viscosity has been revealed.