Publications by authors named "Iain Au-Yong"

The effectiveness of screening programmes is critically dependent on the accuracy of the screening test. Where this relies on clinical expertise, there is an imperative to assure that the level of expertise meets expected standards. In cancer screening involving images, the focus is on the reader.

View Article and Find Full Text PDF
Article Synopsis
  • Mucinous colorectal adenocarcinoma is a rare type of colorectal cancer characterized by the presence of mucinous components in the tumors.
  • While pulmonary metastases are common in both mucinous and non-mucinous colorectal adenocarcinomas, the presentation of these metastases can be different.
  • The study presents three cases where low-density pulmonary metastases were initially misunderstood as benign lesions, highlighting the need for radiologists to recognize that mucinous metastases can appear similar to benign nodules on CT scans.
View Article and Find Full Text PDF

Unlabelled: The National Optimal Lung Cancer Pathway recommends rapid progression from abnormal chest X-rays (CXRs) to CT. The impact of the more rapid reporting on the whole pathway is unknown. The aim of this study was to determine the impact of immediate reporting of CXRs requested by primary care by radiographers on the time to diagnosis of lung cancer.

View Article and Find Full Text PDF

Background Radiographic severity may help predict patient deterioration and outcomes from COVID-19 pneumonia. Purpose To assess the reliability and reproducibility of three chest radiograph reporting systems (radiographic assessment of lung edema [RALE], Brixia, and percentage opacification) in patients with proven SARS-CoV-2 infection and examine the ability of these scores to predict adverse outcomes both alone and in conjunction with two clinical scoring systems, National Early Warning Score 2 (NEWS2) and International Severe Acute Respiratory and Emerging Infection Consortium: Coronavirus Clinical Characterization Consortium (ISARIC-4C) mortality. Materials and Methods This retrospective cohort study used routinely collected clinical data of patients with polymerase chain reaction-positive SARS-CoV-2 infection admitted to a single center from February 2020 through July 2020.

View Article and Find Full Text PDF

Purpose: Critically ill patients with coronavirus disease 2019 (COVID-19) are at increased risk of thrombosis. There are limited data on PE rates in COVID-19 patients at presentation to the emergency department (ED). In this study, we evaluated the detection rates of PE in patients presenting to the ED with suspected and proven COVID-19.

View Article and Find Full Text PDF

Pseudoaneurysms related to the superior mesenteric artery (SMA) are a recognised complication of trauma to the vessel, and successful treatment with stenting has been previously described. We report the case of a patient who presented with obstruction of the fourth part of the duodenum secondary to a traumatic pseudoaneurysm, a hitherto unreported variant of superior mesenteric artery syndrome. Exclusion of the pseudoaneurysm and relief of the duodenal obstruction were simultaneously achieved by placement of a covered stent.

View Article and Find Full Text PDF

Objective: Brown adipose tissue (BAT) is present in adult humans where it may be important in the prevention of obesity, although the main factors regulating its abundance are not well established. BAT demonstrates seasonal variation relating to ambient temperature and photoperiod in mammals. The objective of our study was therefore to determine whether seasonal variation in BAT activity in humans was more closely related to the prevailing photoperiod or temperature.

View Article and Find Full Text PDF

Brown tumors of hyperparathyroidism are rare but can mimic metastatic disease on many imaging modalities. We report the case of a patient presenting with symptomatic brown tumors of hyperparathyroidism due to a large retrosternal parathyroid adenoma, with histopathological correlation of both. The initial imaging findings on plain radiography, computed tomography, and bone scintigraphy were nonspecific and difficult to differentiate from the more common diagnosis of metastatic disease.

View Article and Find Full Text PDF

Spontaneous atlantoaxial dislocation is a rare recognised complication of Down syndrome. In the majority of cases, dislocation takes place in an anteroposterior direction and is often associated with abnormalities of odontoid development or ossification. Rotatory atlantoaxial dislocation is extremely rare in Down syndrome and this is to our knowledge the first reported case in which modern imaging methods have been described; surface shaded reformats derived from a multislice CT scan were of fundamental importance in making the diagnosis.

View Article and Find Full Text PDF

Aspects of decision making, postoperative management, and complications routinely discussed with patients were investigated using a questionnaire completed by 141 hand surgeons of various grades who regularly manage Dupuytren disease. This account presents the results of this questionnaire study, and the literature is discussed in context. A brief description of operative technique in fasciectomy and dermofasciectomy is included.

View Article and Find Full Text PDF

Lymphoepithelial cysts are rare pancreatic lesions. This case report describes the first excision of such a lesion by laparoscopic distal pancreatectomy which is a recognized procedure for treatment of cystic pancreatic neoplasms. Our patient underwent complete excision of the lesion and has enjoyed complete resolution of his symptoms.

View Article and Find Full Text PDF