Potentially Inappropriate Medication Use Among Institutionalized Older Adults at Nursing Homes in Puerto Rico.

Prevalence of potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs). Cross-sectional study through review of residents' records. Three nursing homes of Puerto Rico's metropolitan area.

Incidence and Preventability of Medication Errors and ADEs in Ambulatory Care Older Patients.

Objective: To assess the incidence of medication errors, adverse drug events (ADEs), and potential ADEs (poADEs) in patients 65 years of age and older.

Design: This is a retrospective cohort study (2011 to 2014).

Setting: The study was performed at a section 330 federally funded ambulatory health care center.

Prediction of warfarin dose reductions in Puerto Rican patients, based on combinatorial CYP2C9 and VKORC1 genotypes.

Background: The influence of CYP2C9 and VKORC1 polymorphisms on warfarin dose has been investigated in white, Asian, and African American populations but not in Puerto Rican Hispanic patients.

Objective: To test the associations between genotypes, international normalized ratio (INR) measurements, and warfarin dosing and gauge the impact of these polymorphisms on warfarin dose, using a published algorithm.

Methods: A retrospective warfarin pharmacogenetic association study in 106 Puerto Rican patients was performed.