[Efficiency of teeth local anesthesia by articaine-containing formulation with adrenaline and clonidine in pediatric dentistry].

The study evaluated duration and depth of the local infiltration anesthesia by articaine with different combinations of epinephrine and clonidine : articaine (4%) + epinephrine (1: 200 000), articaine (4%) + clonidine (1:100 000), articaine (4%) + epinephrine (1:200 000) + clonidine (1:100 000), articaine (4%) + epinephrine (1: 400 000) + clonidine (1:100, 000) in pediatric dental practice. It was revealed that the replacement of the vasoconstrictor epinephrine on clonidine associated with reduced depth and duration of analgesia. This increased efficiency is provided by inclusion of epinephrine (1:200 000), and clonidine (1:100 000) into anesthetic solution, which provided statistically significant increase in depth and duration of anesthesia.

[Efficacy of the use of antioxidant preparation mexidol in comprehensive treatment of inflammatory diseases of parodontium].

Examination of 90 patients (52 women and 38 men) in the age range from 25 to 60 with chronic generalized parodontitis of medium severity was done. All examined were divided into 4 groups; 1st - was control, in 3 of them antioxidant preparation mexidol in different forms was used, the. The exercised comprehensive study and treatment of the mentioned above pathology of medium severity with the use of mexidol let us conclude that in comprehensive therapeutical treatment it is necessary to include not only local but also general mexidol use.