[Experimental prophylactic and prospective epidemiological studies of ischemic heart disease in Kaunas].

The authors report on the data of two epidemiological investigations of ischaemic heart disease (IHD) that were undertaken in Kaunas (Kaunas-Rotterdam Intervention Study 1972 - 1974) to study the efficacy of the multifactorial prevention of IHD. The comparison of the screening data of representative selections in men 45-59 years no significant spread of IHD and its risk factors have been found. On the strength of the data of prospective observation of selection of the first investigation a statistically significant relationship between the risk factors and the spread of the stenosing atherosclerosis in the coronaries have been recorded.