[Modifying effect of low-intensive electromagnetic radiation on the irradiated cells].

The normalising effect of low-intensive electromagnetic radiation on the viability of cell culture of L929 line, irradiated with gamma-quantums of 137Cs in a wide dose range was demonstrated.

[The cytotoxic effect of heavy metals on an L-cell culture].

The dependence of some parameters of L-cells culture viability on different concentrations of heavy metals was studied. Considerable cytotoxic effect of low concentrations of nickel (0.025 mcg/ml) and lead (0.

[Protein phosphorylation and activity of insulin and epidermal growth factor receptors in liver plasma membranes of rats kept in the zone of the accident at the Chernobyl nuclear power station].

Disruption in transfer of regulatory signal from insulin and EGF receptors in liver plasma membrane of rats, their 3 generation being kept in the Chernobyl accident 30-km zone has been found. As in case with imbalance in hormone binding and receptor phosphorylation of insulin receptors in experimental diabetes mellitus, an increasing of insulin and EGF binding by appropriate receptors with simultaneous decrease of its protein kinase activity after ligand binding was shown in rats chronically irradiated in the 30-km accident zone.

[The reaction of rat blood plasma to gamma radiation studied by the use of laser photon-correlation spectroscopy].

Using the method of laser photon correlation spectroscopy it was shown that the typical pattern of distribution of blood plasma (BP) particles according to their sizes, characteristic of intact animals, was asymmetric with regard to a mean value. Gamma irradiation with sublethal doses was shown to change essentially the pattern of BP distribution. For instance, in BP of exposed animals, the number of particles of much smaller sizes increased as compared to that in intact animals.

[The biological effects in animals in relation to the accident at the Chernobyl Atomic Electric Power Station. 11. The ultrastructure of the bone marrow cells in different generations of rats].

In studying the bone marrow cell ultrastructure in male rats (F0-F2 generations) aged 3 months, which were brought up within the thirty kilometer Chernobyl A.P.S.

[The biological effects in animals in relation to the accident at the Chernobyl Atomic Electric Power Station. 10. Cooperative immune reactions in different generations of mice].

The immune status of mice has been assessed by the whole complex of data. The permanent action of low-level radiation has been shown to suppress considerably the rate of reactions of the delayed-type hypersensitivity and "graft versus host" disease, as well as NK and specific cytolytic T-lymphocyte activity. The dynamics of accumulation and the levels of antiviral antibodies in the serum, lung and trachea extracts are virtually invariable.

[The biological effects in animals in relation to the accident at the Chernobyl Atomic Electric Power Station. 9. The morphofunctional indices of the immunocompetent organs in mice].

The permanent action of small doses of low-intensity radiation on the immune status of 2.5-3.5 month CC57W mice has been investigated.

[The biological effects in animals in relation to the accident at the Chernobyl Atomic Electric Power Station. 8. The status of cellular immunity in different generations of rats].

In studying immunity in laboratory rats of different generations (P, F1 and F2) brought up in Chernobyl in 1989-1990 the authors have revealed the development of leuko- and lymphopenia; decrease in the absolute content of immunocompetent cells bearing Fc receptors to IgG; stable and long-lasting suppression of blood NK cell activity; reduction of antibody-dependent cytotoxicity; and changed ability of blood lymphocytes to interact contactly with allogenic mast cells. The most considerable disorders have been found in 6- and 9-month-old F1 rats and in 3- and 6-month-old F2 rats.

[The biological effects in animals related to the accident at the Chernobyl Atomic Electric Power Station. 6. The physiological development and cytogenetic indices of the progeny of rats].

Certain alterations have been revealed in the postnatal ontogenesis parameters of albino mongrel rats and their descendants constantly kept within the thirty-kilometer zone of the Chernobyl A.P.S.

[The biological effects in animals in relation to the accident at the Chernobyl Atomic Electric Power Station. 5. Longevity and the carcinogenic effects].

Remote effects in laboratory animals living in conditions of exposure to a mixture of external and internal radiation resulted from the Chernobyl A.P.S.

[The biological effects in animals in relation to the accident at the Chernobyl Atomic Electric Power Station. 3. The morphological and ultrastructural changes in the lungs of rats].

The morphological and ultrastructural changes revealed in the lungs of rats kept within the Chernobyl accident zone during the period of 6 to 24 months were shown to be uniform and multicomponent. The changes were found both in the respiratory and the vascular connective tissue. The inflammatory processes occurred with formation of pneumonic foci, hypo- and disatelectasis, emphysematous changes, impairment of interalveolar septa, and connective tissue cell proliferation.

[The biological effects in animals related to the accident at the Chernobyl Atomic Electric Power Station. 2. The state of bone marrow hematopoiesis in rats].

It has been shown that rats born during the first months after the Chernobyl A.P.S.

[The biological effects in animals related to the accident at the Chernobyl Atomic Electric Power Station. 1. The experimental model. The radiation loads on animals kept continuously under external and internal radiation exposure in the area of the Chernobyl Atomic Electric Power Station].

Irradiation conditions in which laboratory animals were kept in experimental laboratories of Chernobyl and Kiev after the accident at the Chernobyl A.P.S.

[The biological effects in animals related to the accident at the Chernobyl Atomic Electric Power Station. 4. The morphological and ultrastructural changes in the liver of rats].

A study was made of the morphological and ultrastructural changes in hepatic tissue of rats lived within the Chernobyl accident zone during the period of 6 to 25 months. Considerable nonspecific changes in hepatocytes (fatty, vacuolar and parenchymatous degeneration, and hepatocyte necrobiosis) were seen throughout the entire period of observation. Coagulation necrosis of certain hepatocytes, Kupffer and endothelial cells, and the development of microcholangiomas by the end of the second year were the most characteristic alterations.

[Circadian and seasonal rhythms in the radiosensitivity of mongrel white rats].

From experiments in albino mongrel rats it is shown that the radiosensitivity of gamma-irradiated (60Co) animals follows a daily rhythm. A synchronization of the daily rhythms in radiosensitivity was noted in winter and during the first spring month which was impaired in April. Established were the rhythms of radiosensitivity for three seasons, i.

[Formation of a fast-neutron beam for radiobiological experiments on the U-240 isochronous cyclotron and a study of its dosimetric characteristics].

The paper submits the description of the channel equipped for radiobiological experiments with fast neutrons at the isochronous cyclotron U-240. A study was made of some dosimetric characteristics of a mixed gamma-and-neutron beam.

[Chemiluminescence of hemoglobin induced by hydrogen peroxide].

A new chemiluminescent hemoglobin (H2O2 + KOH) system is suggested. It is characterized by a comparatively high luminescence intensity. The chemiluminescence is shown to depend on the availability of hemoglobin and H2O2 in a cell.