[Minor fatty acids of biological fluids of urogenital organs and their significance in the diagnosis of inflammatory processes].

Minor lipid components (less than 1%), not occurring in the cells of mammals, have been detected in the profile of fatty acids (FA) in urine and vaginal fluid in females, as well as in ejaculate in males, by the method of gas chromatography and mass spectrometry. Their origin is supposedly attributed to microorganisms colonizing urogenital organs under normal conditions and in infectious pathology. Minor FA in the biological fluids of the urogenital tract (UGT) in man are compared with the FA composition of pure microbial cultures.

[The adaptational properties and immunoregulatory action of a preparation of proteolytic enzymes in experimental stress].

The use of the experimental model of the development of acute secondary immunodeficiency, accompanied by the redistribution of immunoglobulins from plasma to blood cells, for evaluating the effect of immunomodulation is substantiated. The preparation of proteolytic enzymes Wobenzym [correction of "Vobenzyme"] has been shown to produce significant and dose-dependent decrease the sorption of immunoglobulins on mouse cells in the process of swimming.

[Hair analysis for evaluation of selenium status in Managua population (Nicaragua)].

Mean hair selenium of Managua citizens--743 mg/kg--was higher than of Moscow citizens. Significant differences were detected between groups of citizens with different social sighs: those with low income and perhaps irrational nutrition possess hair selenium value smaller (598 +/- 46 mg/kg) than those with relatively high income (713 +/- 40 mg/kg). Among recent country emigrants hair selenium was round to be the highest--898 +/- 60 mg/kg.

[Level of selenium supply for inhabitants of the Northern economic area of Russia].

Human selenium levels were estimated in 28 towns and settlements of the Murmansk, Vologda, Arkhangelsk regions and Karelia. These were found to be 90-102 micrograms/l in these areas, the lowest ones being detected in Petrozavodsk. Kondopoga, Suoyarvi, and Kovdor, the highest in Kola.

[A radioimmunological method for determining IgA-class antimeningococcal secretory antibodies in human saliva].

The data on the content of secretory IgA antibodies to group A Neisseria meningitidis protein antigen in the saliva of persons, both having had contact with N. meningitidis culture and having had no such contact, are presented. The results were obtained by the method of radioimmunoassay, developed specially for the determination of N.

[Cellular glucocorticoid reception in man and differences in type of reaction to stress].

Three groups of individuals were investigated, which differed in constitution and reaction to stress. Group I comprised randomly selected individuals. Groups II and III were formed of highly qualified athletes, weight lifters and marathoners who matched those from Group I.

[Dynamics of the level of antibodies to protein antigens of the Meningococcus serogroup A in the serum of patients with meningococcal infection].

Two characteristics were determined in the sera of patients by means of radioimmunoassay (RIA) techniques: the RIA titer and the characteristic indicating the presence of highly avid antibodies in the serum. This investigation revealed that in the sera of patients with meningococcal infection of moderate severity the values of the RIA titer of IgM, IgG and IgA, as well as the values indicating the levels of highly avid IgM, IgG and IgA, increased as the infection progressed. In patients with the severe form of meningococcal infection the values of the RIA titer of IgA and IgA increased, while the RIA titer of IgG remained practically unchanged.

[Immunohormonal homeostasis in meningococcal meningitis].

The examination of 18 patients with meningococcal infection has revealed the presence of reciprocal relationships between changes in the content of cortisol and triiodothyronine in their blood, especially at the beginning of the disease. The dynamics of changes in the concentration of rosette-forming cells has proved to be similar to that of changes in the concentration of triiodothyronine. A decrease in the level of thyroid hormones in the blood has been observed in experimental infections and oncological processes in mice, rats or guinea pigs, as well as after the injection of adjuvants into these animals.

[Comparative iodination of a series of allergens].

The study of 27 allergens, carried out with the use of the standard technique of chloramine iodination by Hunter's method, revealed that the biological properties of the allergens were not essentially related to their capacity for binding 125I, this capacity being, on the whole, low. The blood sera of patients with allergic diseases were found to be no different from the blood sera of healthy persons in their capacity for binding 125I.

[Substrate reaction concentration in chloramine iodination].

The conditions of chloramine iodization of peptides of different nature have been systematically studied. The empirical formula permitting the calculation of the optimal aliquot of polypeptide without additional experiments is proposed; this method ensures the saturation of peptide molecules with iodine approximately to a level of 1 iodine atom per molecule.

[Study of the somatotropic function of the pituitary gland and the glucocorticoid function of the adrenal glands in rats with alloxan diabetes].

The somatotropichormone (STH) content was studied in the hypophysis and the peripheral blood of rats with alloxan diabetes; the corticosterone content was determined in their peripheral blood. The STH content in the peripheral blood and the hypophysis of these rats failed to differ from that in the control group, but the blood STH content rose considerably in the sick animals. Exclusion of the insular apparatus function was accompanied by the adrenal gland hypertrophy, which correlated with the rise of the blood corticosterone level.

[Radiocompetitive method of H antigen determination].

The authors describe a radiocompetitive method of H-d-monomere determination with the sensitivity of 2 ng/ml in double antibodies modification; this method was used for comparing the immunological affinity of the affiliated H-antigens. A difference between the immunological affinity to the antibodies in a monomere, polymere and the flagellum was shown.

[Combinatorial relations in the EEG spectrum].

The geometric mean frequency of any EEG wave divides its frequency band B into sub-bands b and s. For the wave beta the values s, b and B are the subsequent elements of the geometric progression with denominator equals to the invariant of the gold section. A hypothesis was proposed that all the EEG waves were described by the system SG of the recurrence equations.

[Assessment of the somatotropic function of the hypophysis in patients with hypophyseal nanism and gonadal dysgenesis by using the insulin-tolerance and arginine-tolerance tests].

With the aid of insulin-tolerance and arginine tolerance tests (ITT and ATT, respectively) somatotropic function of the hypophysis was assessed in 18 patients with hypophyseal nanism and in 12--with gonad dysgenesis. A marked delay in development and a premature exhaustion of the STH secretion was noted in the patients wiht hypophyseal nanism. In patients with gonad dysgenesis the STH secretion was somewhat redeced during the ITT.