Publications by authors named "I-Wen Lai"

Purpose: To evaluate the association between contrast sensitivity (CS), vessel density (VD), and functional parameters in patients with glaucoma of varying severity.

Methods: Ninety-four eyes of 94 patients (57 men and 37 women, aged 56.52 ± 11.

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Background: Previous research on the factors associated with surgical dose-response in strabismus surgery for exotropia has yielded inconsistent results. This study determined the factors influencing surgical dose-response in exotropia patients who underwent recession and resection (R&R).

Methods: Exotropia patients who underwent unilateral R&R at the National Taiwan University Hospital between 2006 and 2021 were evaluated.

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Purpose: To demonstrate the changes in the retinal nerve fiber layer (RNFL) after orbital decompression for thyroid eye disease (TED).

Methods: We retrospectively enrolled 52 surgical TED patients, 30 nonsurgical TED patients, and 30 control subjects. Five surgical TED eyes with disc edema were excluded.

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Purpose: To assess ocular involvement in sarcoidosis and to analyze the manifestations of ocular sarcoidosis (OS) in Taiwan.

Methods: A retrospective review was performed in 364 patients diagnosed as sarcoidosis at National Taiwan University Hospital from 2015 to 2019. The OS diagnosis was based on the revised criteria of International Workshop on Ocular Sarcoidosis.

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Purpose: Kabuki syndrome (KS) is a rare congenital disorder characterized by multiple systemic anomalies and unique facial characteristics. Here, we present the first case, to the best of our knowledge, of bilateral congenital corneal opacities as an early-onset ocular manifestation of KS associated with a KMT2D gene mutation.

Methods: The proband is a girl.

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Article Synopsis
  • Methylmalonic acidemia (MMA) is a rare genetic metabolic disorder that can lead to severe neurological and kidney issues.
  • A unique case is described where a 13-month-old boy with MMA experienced life-threatening hyperkalemia (high potassium levels) and arrhythmia during anesthesia for a port-a-cath insertion.
  • After urgent medical intervention, the patient fully recovered neurologically within a week, highlighting the need to consider hyperkalemia when treating MMA patients with specific heart rhythm problems.
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