Publications by authors named "I-Hsiu Su"

Article Synopsis
  • Changes in cell size significantly affect cell function and the overall integrity of organs, yet the mechanisms of size regulation remain unclear.
  • Researchers used a zebrafish model with inducible folate deficiency (FD) to explore how this condition leads to liver cell enlargement and increased stiffness, linking it to specific cellular pathways (RIPK3/MLKL and Hippo signaling).
  • Findings suggested that FD not only promotes cell growth but also triggers liver inflammation and alters actin structures, highlighting the complex interactions between nutrient status, cellular signaling, and inflammation in maintaining proper cell size.
View Article and Find Full Text PDF

Gram-negative bacteria (GNBs) are common pathogens causing severe sepsis. Rapid evaluation of drug susceptibility would guide effective antibiotic treatment and promote life-saving. A total of 78 clinical isolates of 13 Gram-negative species collected between April 2013 and November 2013 from two medical centers in Tainan were tested.

View Article and Find Full Text PDF

To investigate the effects of dietary methionine restriction (MetR) and endurance exercise on bone quality under a condition of estrogen deficiency, female Sprague-Dawley rats (36-wk-old) were assigned to a sham surgery group or one of five ovariectomized groups subjected to interventions of no treatment (Ovx), endurance exercise (Exe), methionine restriction (MetR), methionine restriction plus endurance exercise (MetR + Exe), and estrogen treatment (Est). Rats in the exercise groups were subjected to a treadmill running regimen. MetR and control diets contained 0.

View Article and Find Full Text PDF