Bioactive Components from with Antioxidant, Anti-α-Glucosidase, and Antiacetylcholinesterase Activities.

The dried root of (Thunb.) Makino (.) is a traditional medicine used to treat fever, pain, and wound healing.

A gender-specific COMT haplotype contributes to risk modulation rather than disease severity of major depressive disorder in a Chinese population.

Background: COMT rs4680 Val158 allele is associated with high MB-COMT protein expression and elevated activity compared to the Met158 allele in post-mortem brains. A meta-analysis study suggested the link between COMT SNPs and MDD risk; in addition, MB membrane-bound (MB-COMT) specific genetic variation was reported that influences predisposition to depression amongst females.

Methods: Four tagSNPs, including rs4680, were genotyped.