Publications by authors named "I-Chin Wei"
Article Synopsis
- Rheumatoid arthritis (RA) is an autoimmune disease that leads to chronic inflammation of joints and tissues, and gut microbiota changes may play a key role in immune dysfunction associated with RA.
- Treatments for RA may influence gut microbiota diversity, suggesting that maintaining or modifying gut bacteria could be an important strategy for managing the disease.
- In a study, B. coagulans BACO-17 showed promise as a new treatment by reducing symptoms of RA and protecting joint tissues, indicating its potential for further research as a therapeutic option.
Osteosarcoma is a malignant tumor with high metastatic potential, such that the overall 5-year survival rate of patients with metastatic osteosarcoma is only 20%. Therefore, it is necessary to unravel the mechanisms of osteosarcoma metastasis to identify predictors of metastasis by which to develop new therapies. Fibroblast growth factor 2 (FGF2) is a growth factor involved in embryonic development, cell migration, and proliferation.
View Article and Find Full Text PDFOsteosarcoma, one of primary bone tumor in children and young adults, has poor prognosis and drug resistances to chemotherapy. In order to reinforce the conventional therapies and antagonize the osteosarcoma in patients, a novel strategy is required for developing a new treatment. In this study, surfactin, a natural product from Bacillus subtilis, showed the efficiency of cell death in osteosarcoma, but not in normal cells.
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