Publications by authors named "I-Cheong Choi"

Despite being widely utilized to help endoscopists identify gastrointestinal (GI) tract diseases using classification and segmentation, models based on convolutional neural network (CNN) have difficulties in distinguishing the similarities among some ambiguous types of lesions presented in endoscopic images, and in the training when lacking labeled datasets. Those will prevent CNN from further improving the accuracy of diagnosis. To address these challenges, we first proposed a Multi-task Network (TransMT-Net) capable of simultaneously learning two tasks (classification and segmentation), which has the transformer designed to learn global features and can combine the advantages of CNN in learning local features so that to achieve a more accurate prediction in identifying the lesion types and regions in GI tract endoscopic images.

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Background And Objective: A deep learning-based intelligent diagnosis system can significantly reduce the burden of endoscopists in the daily analysis of esophageal lesions. Considering the need to add new tasks in the diagnosis system, a deep learning model that can train a series of tasks incrementally using endoscopic images is essential for identifying the types and regions of esophageal lesions.

Method: In this paper, we proposed a continual learning-based esophageal lesion network (CLELNet), in which a convolutional autoencoder was designed to extract representation features of endoscopic images among different esophageal lesions.

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It is challenging for endoscopists to accurately detect esophageal lesions during gastrointestinal endoscopic screening due to visual similarities among different lesions in terms of shape, size, and texture among patients. Additionally, endoscopists are busy fighting esophageal lesions every day, hence the need to develop a computer-aided diagnostic tool to classify and segment the lesions at endoscopic images to reduce their burden. Therefore, we propose a multi-task classification and segmentation (MTCS) model, including the Esophageal Lesions Classification Network (ELCNet) and Esophageal Lesions Segmentation Network (ELSNet).

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The automatic analysis of endoscopic images to assist endoscopists in accurately identifying the types and locations of esophageal lesions remains a challenge. In this paper, we propose a novel multi-task deep learning model for automatic diagnosis, which does not simply replace the role of endoscopists in decision making, because endoscopists are expected to correct the false results predicted by the diagnosis system if more supporting information is provided. In order to help endoscopists improve the diagnosis accuracy in identifying the types of lesions, an image retrieval module is added in the classification task to provide an additional confidence level of the predicted types of esophageal lesions.

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Background: Non-alcoholic steatohepatitis (NASH) is an advanced form of non-alcoholic fatty liver disease (NAFLD) for which there is yet any standard pharmacotherapy. Traditional Chinese medicine formula such as Qushihuayu (QSHY) composing of multiple bioactive compounds has been used to treat NAFLD and NASH and shows beneficial effects over single compound treatment. This study aimed to investigate the mechanism of hepatoprotective effect of QSHY formula using a rat model.

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Background: Gastric intestinal metaplasia (GIM) is a precancerous lesion of gastric cancer. Currently, diagnosis of GIM is based on the experience of a physician, which is liable to interobserver variability. Thus, an intelligent diagnostic (ID) system, based on narrow-band and magnifying narrow-band images, was constructed to provide objective assistance in the diagnosis of GIM.

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In parallel with the prevalence metabolic syndrome, nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease in most countries. It features a constellation of simple steatosis, nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and even hepatocellular carcinoma. There are no approved drugs for effective management of NAFLD and NASH.

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