Publications by authors named "I van Langeveld"

Article Synopsis
  • The study looked at how safe it is for Physician Assistants to give sedation to kids during painful medical procedures like bone marrow tests.
  • They checked if any kids had problems like low oxygen levels or needed extra help breathing during the process.
  • The results showed that there were no serious issues and only a few minor problems, which suggests that it can be done safely by trained Physician Assistants.
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Intestine barrier disruption and bacterial translocation can contribute to sepsis and multiple organ failure, leading causes of mortality in burn-injured patients. In addition, findings suggest that ethanol (alcohol) intoxication at the time of injury worsens symptoms associated with burn injury. We have previously shown that interleukin-22 (IL-22) protects from intestinal leakiness and prevents overgrowth of gram-negative bacteria following ethanol and burn injury, but how IL-22 mediates these effects has not been established.

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Despite improvements in early treatment, survival following burn injury remains challenged by sepsis and multiple organ dysfunction syndrome (MODS). Additionally, susceptibility to infections and growing antibiotic resistance places burn patients at increased risk for infections with multiple-drug resistant organisms (MDROs). We therefore aimed to evaluate the impact of MDRO infections on survival and hospital length of stay, as well as examine the role of these organisms in the development of complications, such as acute kidney injury, sepsis, and MODS.

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