Publications by authors named "I dos-Santos-Silva"
Purpose: In Sub-Saharan Africa (SSA), breast cancer survivors' (BCS) quality of life (QoL) remains understudied. We compared QoL in BCS to cancer-free (CF) women across SSA settings with different levels of development, healthcare systems, ethnic compositions, and HIV prevalence.
Methods: In 2022-2023, all 5 + year BCS from the African Breast Cancer-Disparities in Outcomes study and age-matched CF women from the community setting answered the WHOQOL-BREF questionnaire in Namibia, Nigeria, and Uganda.
Article Synopsis
- Elevated mammographic density (MD) is a significant risk factor for breast cancer, and this study investigates how factors like childbirth, age at first birth, and breastfeeding relate to MD in a large group of women across different countries.
- The research analyzed data from 11,755 women aged 35-85 years, focusing on how factors such as the number of births and the timing of the first birth influence measurements of MD.
- The findings suggest that having more children decreases MD, while older age at first birth is linked to higher MD, particularly in post-menopausal women, highlighting the complex relationships between reproductive factors and breast density.
Purpose: Survival from esophageal cancer (EC) is poor, partly reflecting the delay in diagnosis. To inform the potential measures for downstaging the disease, we estimated diagnosis delay, that is, the length of interval from symptom-to-diagnosis (STD), and investigated its correlates among patients with EC in a high-risk resource-limited rural area in China.
Methods: Patients newly diagnosed with EC (N = 411) were recruited in a secondary hospital in Henan province in China between August 1, 2018, and October 21, 2020.
Background: Breast cancer (BC) is the leading cause of cancer-related morbidity and mortality in women living in South Africa, a country with a high HIV burden. However, characteristics of the double burden of HIV and BC in South Africa have not been properly investigated. We described characteristics of BC cases by HIV status in South Africa.
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- - The study investigates how geographical factors impact breast cancer survival rates in sub-Saharan Africa, highlighting the need for improved healthcare access in these regions.
- - Researchers analyzed data from over 2,000 women diagnosed with breast cancer, revealing that those in rural areas had significantly lower 4-year survival rates (39%) compared to those in urban areas (49%).
- - Findings indicate that women living more than an hour from a hospital faced even worse outcomes, emphasizing the urgent need for interventions to address these healthcare disparities.