[Childhood acute lymphoid leukemia relapsing in adult age?].

A 30-years-old woman developed an acute lymphoblastic leukemia 16 years after a successfully treated childhood acute lymphoblastic leukemia. The developed second malignancy unexpectedly seemed identical to her previous malignant disease. That's why and because of the literature doesn't mention acute lymphoblastic leukemia as a second neoplasm after an acute lymphoblastic leukemia we considered the disease unusual late relaps of the original childhood malignancy.

Pregnancies and offspring in survivors of acute lymphoid leukemia and lymphoma.

Since few data on the reproductive outlook of patients successfully treated for lymphoproliferative disease are available, further experiences on the pregnancy outcome and offspring follow-up of 12 women treated for acute lymphoid leukemia and 7 women treated for malignant lymphoma are reported. Of the 20 pregnancies of leukemic patients in remission, 14 ended in live births, one in spontaneous abortion, and 5 in elective abortions among which one was performed during relapse. One minor (hip dysplasia) and one major birth defect (Apert syndrome) were seen.

Age dependency of the progression of HIV disease in haemophiliacs; predictive value of T cell subset and neopterin measurements.

Sixteen HIV-seropositive haemophiliacs were followed up for 42 months and 9 other patients for 24 months. All patients were infected in 1983 or 1984. T cell subsets and serum neopterin levels were measured twice a year.

[Pregnancy in acute lymphoid leukemia].

Authors followed up 5 girls, aged 7 to 13 years suffered of acute lymphoid leukemia, who got into complete remission due to induction therapy with multiple cytostatic agents and who became pregnant after the maintenance treatment lasting two and a half years. Of 8 pregnancies of the 5 women 4 pregnancies were terminated by spontaneous deliveries with mature newborns, and 4 ones were interrupted in gestational weeks 7 to 14. Except for one patient who died one year after the termination of pregnancy the other remained in complete remission during and after the pregnancy, and at present their survival times range between 12.