[Behcet's disease--clinical picture and treatment].

Behcet's disease is a systemic inflammatory disease of unknown etiology which usually occurs as a trait of symptoms: aphatous stomatitis, genital ulcerations and eye disease. Characteristic manifestations are frequent: erythema nodosum, arthralgias, arthritis, myalgias, phlebothrombosis and nervous system disorders as well as disorders of other organs and systems. Behcet's disease was discovered in 1937 for the first time by dermatovenerologist Hulusi Behcet (1889 - 1948) after whom it was named Behcet's disease or Behcet's syndrome.

Reduction of cortisol levels after single intra-articular and intramuscular steroid injection.

Background: This study was undertaken to determine the influence of single intra-articular or intra muscular injections of methylprednisolone acetate on the hypothalamic-pituitary-adrenal axis.

Patients And Methods: Twenty-one patients with rheumatic disease who had never been treated with systemic glucocorticoids and had not received local injections of these agents for the preceding 2 months, were given 40 mg of methylprednisolone acetate. Group I (11 patients) received one intra-articular injection into the knee, and Group II (10 patients) received the same dose intramuscularly.

[Juvenile chronic arthritis in children].

Juvenile chronic arthritis is a descriptive term for a group of illnesses pertaining to children characterized by nonsuppurative inflammation of joints having a chronic course. The term is rather new and comes from a meeting of scientists of the European Society of Rheumatologists (EULAR) and the World Health Organization (WHO), 1977 in Oslo. The cause of illness is unknown.

[Evaluation of the effect of therapy with Turganil in 1,240 patients].

The paper deals with results of investigation on therapy efficiency of tiaprophenic acid (Turganil, Jugoremedia) in the group of 1240 outpatients and hospitalized patients. It was an open clinical experiment, the drug has been applied for six months approximately, and the group consisted of patients with inflammatory, degenerative and outjoint rheumatism and other systemic diseases of the connective tissue. Favorable therapy effects occurred in all investigated groups, being in harmony with other authors' data, while drug tolerance was relatively good.

Presence of oestrogen receptors on target cells and antiproliferative activity of estramustine phosphate: positive correlation for human tumours in vitro.

Incubation with estramustine phosphate for 24 h inhibited DNA, RNA and protein synthesis in primary cultures of human kidney, mammary, prostatic, cervical and endometrial carcinoma. Not only the presence, but also the concentration of oestrogen receptors correlated with estramustine phosphate effects on tumour cell proliferation.