Objectives: Conventional methods of imaging neuroendocrine tumors with computed tomography, magnetic resonance imaging, indium-111-octreotide, or radiolabeled metaiodobenzilguanidine scintigraphy have limitations. This pilot study tried to improve the localization of these tumors with fluorine-18-fluorodihydroxyphenylalanine (F-DOPA) positron-emission tomography (PET) scanning.
Materials And Methods: We studied 22 patients, the majority of whom were referred with clinical diagnosis or suspicion of carcinoid ( = 11), neuroendocrine tumors ( = 7) or pheochromocytoma/paraganglioma (PGL) ( = 4).
A 77-year-old man with Gleason score 7 prostate cancer, after radical prostatectomy, in whom the prostate-specific antigen level increased to 5.0 ng/mL 8 years later, underwent a ProstaScint scan. Radiotracer deposition was noted in the prostatic "fossa," highly suspicious of recurrence.
View Article and Find Full Text PDF