CCR6 T helper cells and regulatory T cells in the blood and gastric mucosa during Helicobacter pylori infection.

Background: Helicobacter pylori (H. pylori) can evade the host's immune response and persist for a long time on the gastric mucosa. T helper (Th) cells appear to be involved in the control of H.

Cytokine Profile of CCR6 T-Helpers Isolated from the Blood of Patients with Peptic Ulcer Associated with Infection.

Unlabelled: We previously found that the number of CCR6 T-helpers with the phenotype of effector/effector memory T cells increases in the blood of patients with -associated peptic ulcer. The mature phenotype and the expression of the chemokine receptor CCR6, which is involved in migration of lymphocytes to the inflamed mucous membrane of the gastrointestinal tract, suggests that these cells are involved in the immune response observed in this clinical condition. To better understand the pathogenetic role of these cells, it is necessary to study their functional activity, specifically, the production of pro-inflammatory cytokines involved in the pathogenesis of the disease.

[COMPARATIVE ANALYSIS OF SYSTEM HUMAN RESOURCES HEALTH CARE IN THE NORTH CAUCASIAN FEDERAL DISTRICT].

The article examines the features of the regional provision of the health care system with personnel on the basis of a comparative assessment, both in terms of quantitative and level indicators of the personnel potential of the industry of the North Caucasian Federal District. In order to identify a real idea of ​​the state of the personnel potential of the region, the indicators of the load on medical workers were studied. Additionally, they were grouped in relation to the average Russian and mid-level levels.

Low-dose influenza vaccine Grippol Quadrivalent with adjuvant Polyoxidonium induces a T helper-2 mediated humoral immune response and increases NK cell activity.

The influenza vaccine Grippol® Quadrivalent (GQ) is a new vaccine, containing the adjuvant Polyoxidonium® and recombinant hemagglutinins from 4 strains of the influenza virus in amount of 5-6 μg of each hemagglutinin per human dose. These doses of antigens are about 3 times less than the standard dose recommended by WHO. We sought to characterize the immune response to the GQ vaccine and to determine the contribution of the adjuvant in this response.

Which McMaster egg counting technique is the most reliable?

This study focuses on the comparison of three selected modifications of the McMaster counting technique, namely the McMaster method modified by Wetzel (W) and Zajíček (Z), as well as the concentration McMaster technique according to Roepstorff and Nansen (R&N). These modifications differ in the weights of faeces examined (W, 2 g/Z, 1 g/R&N, 4 g), flotation solutions (W, NaCl/Z, MgSO(4) + Na(2)S(2)O(3)/R&N, NaCl + glucose), centrifugation (W, none/Z, 2,000 RPM for 2 min and 2,000 RPM for 1 min/R&N, 1,200 RPM for 5 min), number of McMaster chambers investigated (W, 3/Z, 2/R&N, 2), and multiplication factors used (W, 67/Z, 33/R&N, 20). To investigate the sensitivity and reliability of these methods, nematode eggs (Teladorsagia circumcincta) were used.