[Long-term outcomes after endoscopic treatment of patients with Zenker's diverticulum].

Objective: To assess the long-term outcomes after endoscopic treatment of patients with Zenker's diverticulum.

Material And Methods: A single-center retrospective study included 207 patients with Zenker's diverticulum who underwent surgery between July 2014 and November 2021. There were 213 interventions including surgeries for recurrence.

Phosphorylation of Zearalenone Retains Its Toxicity.

Microbial biotransformation of Zearalenone (ZEN) is a promising deactivation approach. The residual toxicity and stability of Zearalenone-14-phosphate (ZEN-14-P) and Zearalenone-16-phosphate (ZEN-16-P), two novel microbial phosphorylation products of ZEN, remain unknown. We investigated the cytotoxicity, oxidative stress, proinflammatory, and estrogenic activity of phosphorylated ZENs using porcine intestinal cells, uterine explants, and human endometrial cells and traced their metabolic fate by liquid chromatography-tandem mass spectrometry (LC-MS)/MS analysis.

Galileo and BeiDou AltBOC Signals and Their Perspectives for Ionospheric TEC Studies.

For decades, GNSS code measurements were much noisier than phase ones, limiting their applicability to ionospheric total electron content (TEC) studies. Ultra-wideband AltBOC signals changed the situation. This study revisits the Galileo E5 and BeiDou B2 AltBOC signals and their potential applications in TEC estimation.

Differential phase contrast STEM image calculation software - Magnifier.

An innovative software with a user-friendly interface for calculation of differential phase contrast (DPC) scanning transmission electron microscopy images (integrated iDPC- and differentiated dDPC-STEM) is presented. The underlying algorithm is described and the program functionalities are demonstrated on the examples of LiOsO, α-GaO, and LiCoO. The software supports interpretation of DPC-STEM images, which is crucial for qualitative and quantitative analysis of crystal structures and defects.

Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample.

Analyses of ancient DNA typically involve sequencing the surviving short oligonucleotides and aligning to genome assemblies from related, modern species. Here, we report that skin from a female woolly mammoth (†Mammuthus primigenius) that died 52,000 years ago retained its ancient genome architecture. We use PaleoHi-C to map chromatin contacts and assemble its genome, yielding 28 chromosome-length scaffolds.