Publications by authors named "I Weng Lao"
Article Synopsis
- Malnutrition is a significant risk factor for surgical outcomes, particularly in head and neck cancer patients undergoing total laryngectomy with free flap reconstruction, necessitating a focus on preoperative nutritional indicators like prealbumin and albumin levels.
- A review of 83 HNC patients from 2016 to 2022 showed that low preoperative prealbumin levels (≤20 mg/dL) were linked to a higher rate of wound healing complications, with a 33.7% complication rate overall.
- The study concluded that monitoring prealbumin levels and implementing nutritional interventions could potentially reduce complications after surgery.
Astroblastoma is an extremely rare central nervous system tumor characterized by astroblastic pseudorosettes and vascular hyalinization. Despite these histologic hallmarks, its morphology can vary, occasionally resembling other central nervous system tumors such as ependymoma. A novel tumor entity, astroblastoma, meningioma 1 ( MN1 )-altered, has been identified, featuring MN1 gene rearrangements typically involving BEN-domain containing 2 ( BEND2 ) as a fusion partner.
View Article and Find Full Text PDFApart from the lethal midline carcinoma (NUT carcinoma), NUTM1 translocation has also been reported in mesenchymal tumors, but is exceedingly rare. Here, we describe a series of 8 NUTM1 -rearranged sarcomas to further characterize the clinicopathologic features of this emerging entity. This cohort included 2 males and 6 females with age ranging from 24 to 64 years (mean: 51 y; median: 56 y).
View Article and Find Full Text PDFNTRK-rearranged spindle cell neoplasm occurs predominantly in the superficial or deep soft tissues of extremities or trunk. Occurrence in the visceral organs is extremely rare. Herein, we describe 8 cases of NTRK-rearranged spindle cell neoplasm that arose primarily in the gastrointestinal tract.
View Article and Find Full Text PDFObjectives: The purpose of this study is to determine the predictors of neck lymphedema and to explore its association with symptoms and patient-reported outcomes (PROs) in Head and Neck Cancer (HNC) patients who underwent non-operative treatment.
Methods: This study involved a cross-sectional secondary analysis of data from patients diagnosed with head and neck squamous cell carcinoma who underwent radiation therapy (±chemotherapy). Patients with visits <6 weeks or >2 years following completion of radiation and those with recurrent or metastatic cancer were excluded.