Publications by authors named "I Wakabayashi"
[Antithrombotic Action of Alcohol in Relation to Platelet Function].
Nihon Eiseigaku Zasshi
December 2024
The relationship between alcohol consumption and incident ischemic heart disease and stroke is characterized by a J- or U-shape. This denotes that light drinking has a preventive effect on cardiovascular diseases. Effects of alcohol drinking on lipid metabolism including an increase in HDL cholesterol concentration and a decrease in LDL cholesterol concentration are the main reasons for the anti-atherosclerotic action of alcohol.
View Article and Find Full Text PDFObjective: The ratio of γ-glutamyl transferase to HDL-C (GGT/HDL-C) has been proposed as a discriminator of metabolic syndrome. The purpose of this study was to elucidate the relationship between GGT/HDL-C and glycemic status in women.
Methods: The subjects were 18,218 middle-aged women who had received annual health checkups in their workplaces.
Article Synopsis
- Seven low molecular weight peptides were identified as potential biomarkers for diagnosing hypertensive disorders of pregnancy (HDP) and their relationship with leg ischemia and atherosclerosis in patients with lower extremity arterial disease (LEAD) was explored.
- * A study involving 165 outpatients (mainly men) assessed symptoms of leg ischemia and blood flow using the Rutherford classification, ankle-brachial index (ABI), and carotid artery intima-media thickness (IMT).
- * Results indicated that certain peptides (m/z 2091 and 2378) were positively correlated with leg ischemia severity, while peptide m/z 2081 showed an inverse relationship; however, these peptides did not correlate with carotid atherosclerosis.
Article Synopsis
- The study investigates the relationship between serum creatinine and estimated glomerular filtration ratio (eGFR) in relation to hyperuricemia, questioning which is more strongly associated with the condition.
- It analyzed data from 6020 individuals who underwent health check-ups between 2017 and 2021, categorizing them into normuricemia and hyperuricemia groups based on serum uric acid levels.
- Results revealed that higher serum creatinine levels are significantly associated with hyperuricemia in males, likely influenced by factors like muscle mass and diet, while eGFR showed weaker correlation in this context.
Objectives: Cardio-ankle vascular index (CAVI) is a blood pressure-independent measure of heart-ankle pulse wave velocity and is used as an indicator of arterial stiffness. However, there is a paradox that CAVI is inversely associated with leg ischemia in patients with lower extremity arterial disease (LEAD). The aim of this study was to clarify the significance of the absolute value of left and right difference in CAVI (diff-CAVI).
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