Publications by authors named "I Vucenik"
Article Synopsis
- Dietary phytic acid (IP6) was traditionally seen as an antinutrient due to its ability to hinder mineral absorption, but new evidence highlights its potential health benefits like anti-inflammatory and anticancer properties.
- IP6 is found in both plants and human cells and may help prevent harmful conditions like vascular calcification by inhibiting the growth of certain crystals.
- While there are concerns that IP6 might interfere with bone mineralization, recent studies suggest it may actually promote bone health, indicating a need for more research on its effects.
Background:
Objectives: This perspective seeks to explore the mechanisms and functions of
Methods: A narrative review of all the relevant papers known to the authors was conducted.
Phosphorylated inositol hexaphosphate (IP6) is a naturally occurring carbohydrate, and its parent compound, myoinositol (Ins), is abundantly present in plants, particularly in certain high-fiber diets, but also in mammalian cells, where they regulate essential cellular functions. IP6 has profound modulation effects on macrophages, which warrants further research on the therapeutic benefits of IP6 for inflammatory diseases. Here, we review IP6 as a promising compound that has the potential to be used in various areas of dentistry, including endodontics, restorative dentistry, implantology, and oral hygiene products, due to its unique structure and characteristic properties.
View Article and Find Full Text PDFMyo-inositol (myo-Ins) and D-chiro-inositol (D-chiro-Ins) are natural compounds involved in many biological pathways. Since the discovery of their involvement in endocrine signal transduction, myo-Ins and D-chiro-Ins supplementation has contributed to clinical approaches in ameliorating many gynecological and endocrinological diseases. Currently both myo-Ins and D-chiro-Ins are well-tolerated, effective alternative candidates to the classical insulin sensitizers, and are useful treatments in preventing and treating metabolic and reproductive disorders such as polycystic ovary syndrome (PCOS), gestational diabetes mellitus (GDM), and male fertility disturbances, like sperm abnormalities.
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