The association of low birth weight with serum C reactive protein in 3-year-old children living in Cuba: A population-based prospective study.

Objective: Low birthweight is associated with a decreased risk of childhood leukemia and an increased risk of both cardiovascular disease and all-cause mortality in adult life. Possible biological mediators include systemic innate immunity and inflammation. We tested the hypothesis that birthweight was inversely associated with serum high sensitivity C reactive protein assay (hsCRP), a measure of both innate immunity and systemic inflammation.

What are the main environmental exposures associated with elevated IgE in Cuban infants? A population-based study.

Objective: Immunoglobulin E (IgE) plays a key role in allergy disease pathogenesis, but little is known about the environmental factors associated with higher IgE levels in infants. The aim of this study was to determine the risk factors for elevated serum total IgE infants living in Havana.

Methods: Eight hundred and seventy-seven infants provided blood samples.

Risk factors for eczema in infants born in Cuba: a population-based cross-sectional study.

Background: There is a concern that allergic disease in childhood is higher than expected in Cuba. The aim of this study was to determine the risk factors for eczema of infants aged 12-15 months living in Havana.

Methods: We used a cross-sectional epidemiological study design.

Risk factors for wheezing in infants born in Cuba.

Background: Cuba is a unique country, and despite limited economic development, has an excellent health system. However, the prevalence of asthma symptoms in children in Havana, Cuba, is unusually high.

Aim: As early life exposures are critical to the aetiology of asthma, we have studied environmental influences on the risk of wheezing in Cuban infants.